Adipoq (NM_009605) Mouse Recombinant Protein
CAT#: TP721158L
Purified recombinant protein of Mouse adiponectin, C1Q and collagen domain containing (Adipoq)
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Specifications
Product Data | |
Species | Mouse |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Glu18-Asn247
|
Tag | N-His |
Predicted MW | 27.2 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Storage | Store at -80°C. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_033735 |
Locus ID | 11450 |
UniProt ID | Q60994 |
Cytogenetics | 16 13.96 cM |
Refseq Size | 1233 |
Refseq ORF | 741 |
Synonyms | 30kDa; Acdc; Acrp30; Ad; adipo; apM1; APN; GBP28 |
Summary | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.[UniProtKB/Swiss-Prot Function] |
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