Cxcl1 (NM_008176) Mouse Recombinant Protein

CAT#: TP723728

Purified recombinant protein of Mouse chemokine (C-X-C motif) ligand 1 (Cxcl1 / KC)

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CXCL1, the region of Asn29-Lys96, from gene Accession# NM_008176.3
• Tag: Tag Free
• Predicted MW: 7.4 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: Bioactivity was measured by its property to chemoattract human neutrophils in a dose dependent manner.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_032202
• Locus ID: 14825
• UniProt ID: P12850, A2RTH0
• Cytogenetics: 5 44.78 cM
• Refseq Size: 964
• Refseq ORF: 288
• Synonyms: Fsp; gro; Gro1; KC; Mgsa; N51; Scyb1
• Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]