Il6 (NM_031168) Mouse Recombinant Protein

CAT#: TP723747

Purified recombinant protein of Mouse interleukin 6 (Il6)

Specifications

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse IL-6, the region of Phe25-Thr211, from gene Accession# NM_031168
• Tag: Tag Free
• Predicted MW: 21.9 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: Purity is >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: Sodium Acetate and EDTA
• Bioactivity: The ED50 is less than 0.01 ng/ml, corresponding to a specific activity of > 1 x 10^8 units/mg, determined by the dose dependent stimulation of 7TD1 cell proliferation.
• Endotoxin: Less than 0.01 ng per ug protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_112445
• Locus ID: 16193
• UniProt ID: P08505, A2RTD1
• Cytogenetics: 5 15.7 cM
• Refseq Size: 1087
• Refseq ORF: 633
• Synonyms: Il-6
• Summary: This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]