Eotaxin 3 (CCL26) (NM_006072) Human Recombinant Protein

CAT#: TP723818

Purified recombinant protein of Human chemokine (C-C motif) ligand 26 (CCL26 Eotaxin-3)

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Tag: Tag Free
• Predicted MW: 8.4 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >98%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: Bioactivity was measured by its property to chemoattract BaF3-mCCR3 transfectants in a dose dependent manner.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method

Reference Data

• RefSeq: NP_006063
• Locus ID: 10344
• Cytogenetics: 7q11.23
• Refseq Size: 562
• Refseq ORF: 282
• Synonyms: IMAC; MIP-4a; MIP-4alpha; SCYA26; TSC-1
• Summary: This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction