Ccl19 (NM_011888) Mouse Recombinant Protein

CAT#: TP723844

Purified recombinant protein of Mouse chemokine (C-C motif) ligand 19 (Ccl19 / MIP-3beta)

Specifications

Product Data

• Species: Mouse
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CCL19, the region of Gly26-Val107-Leu-Glu, from gene Accession# NM_011888.2
• Tag: Tag Free
• Predicted MW: 9.3 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >95%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS
• Bioactivity: Bioactivity was measured by its property to chemoattract Baf3-hCCR7 transfectants in a dose dependent manner.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_036018
• Locus ID: 24047
• UniProt ID: O70460, Q548P0
• Cytogenetics: 4 A5
• Refseq Size: 720
• Refseq ORF: 324
• Synonyms: CKb11; ELC; exodus-3; MIP3B; Scya19
• Summary: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. [UniProtKB/Swiss-Prot Function]