Ctla4 (NM_009843) Mouse Recombinant Protein

CAT#: TP723873

Purified recombinant protein of Mouse cytotoxic T-lymphocyte-associated protein 4 (Ctla4)

Product Images

Specifications

Product Data

• Species: Mouse
• Expression Host: CHO
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CTLA-4, the region of Ala37-Phe162, from gene Accession# NM_009843
• Tag: Fc chimera
• Predicted MW: 41 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >95%, as determined by Coomassie stained SDS-PAGE
• Buffer: 1 x PBS
• Bioactivity: The ED50 is 70 - 350 ng/ml, corresponding to a specific activity of 0.28-1.4 x 104 units/mg, determined by the dose dependent inhibition of IL-2 production induced by 0.5 µg/ml of CD80 on Jurkat cells
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_033973
• Locus ID: 12477
• UniProt ID: P09793, Q6GTR6
• Cytogenetics: 1 30.58 cM
• Refseq Size: 1933
• Refseq ORF: 669
• Synonyms: Cd152; Ctla-4; Ly-56
• Summary: This gene is a member of the immunoglobulin superfamily, and encodes a protein that functions as a negative regulator of T-cell responses. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]