IL9 (NM_000590) Human Recombinant Protein

CAT#: TP723892

Purified recombinant protein of Human interleukin 9 (IL9)

Specifications

Product Data

• Species: Human
• Expression Host: Sf9
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Human IL-9, the region of Gln19-Ile144, from gene Accession# NM_000590
• Tag: Tag Free
• Predicted MW: 14 kDa
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer
• Purity: >90%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 1 x PBS, pH7.4
• Bioactivity: The ED50 is 0.1-0.5 ng/mL
• Endotoxin: Less than 0.1 EU per µg of protein as determine by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Reference Data

• RefSeq: NP_000581
• Locus ID: 3578
• UniProt ID: P15248
• Cytogenetics: 5q31.1
• Refseq Size: 591
• Refseq ORF: 432
• Synonyms: HP40; IL-9; P40
• Summary: The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Asthma, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway