bcl 6 (BCL6) (NM_001706) Human Recombinant Protein
CAT#: TP750190
Purified recombinant protein of Human B-cell CLL/lymphoma 6 (BCL6), transcript variant 1, Ser209-Pro292, tag free, expressed in E.coli, 50ug
Other products for "BCL6"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Ser209-Pro292) of BCL6
|
Tag | Tag free |
Predicted MW | 9.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001697 |
Locus ID | 604 |
UniProt ID | P41182 |
Cytogenetics | 3q27.3 |
Refseq Size | 3537 |
Refseq ORF | 2118 |
Synonyms | BCL5; BCL6A; LAZ3; ZBTB27; ZNF51 |
Summary | 'The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]' |
Protein Families | Druggable Genome, Transcription Factors |
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