BMP4 (NM_001202) Human Recombinant Protein

CAT#: TP750195

Purified recombinant protein of Human bone morphogenetic protein 4 (BMP4), transcript variant 1, Ser293-End, tag free, expressed in E.coli, 50ug

Product Images

Purified recombinant protein BMP4 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Ser293-End) of BMP4
• Tag: Tag free
• Predicted MW: 13.1 kDa
• Concentration: >50 ug/mL as determined by Bradford protein assay method.
• Purity: > 85% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 10mM Sodium citrate, 10% Glycerol，pH3.50
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001193
• Locus ID: 652
• UniProt ID: P12644, Q53XC5
• Cytogenetics: 14q22.2
• Refseq Size: 1957
• Refseq ORF: 1224
• Synonyms: BMP2B; BMP2B1; MCOPS6; OFC11; ZYME
• Summary: 'This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016]'
• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Secreted Protein, Stem cell relevant signaling - TGFb/BMP signaling pathway
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer, TGF-beta signaling pathway