Apolipoprotein E (APOE) (NM_000041) Human Recombinant Protein
CAT#: TP750215
Purified recombinant protein of Human Apolipoprotein E isoform 1, 19Lys-End, tag free, expressed in E.coli, 50ug
Other products for "APOE"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
1 KVEQAVETEP EPELRQQTEW QSGQRWELAL GRFWDYLRWV QTLSEQVQEE LLSSQVTQEL
61 RALMDETMKE LKAYKSELEE QLTPVAEETR ARLSKELQAA QARLGADMED VCGRLVQYRG 121 EVQAMLGQST EELRVRLASH LRKLRKRLLR DADDLQKRLA VYQAGAREGA ERGLSAIRER 181 LGPLVEQGRV RAATVGSLAG QPLQERAQAW GERLRARMEE MGSRTRDRLD EVKEQVAEVR 241 AKLEEQAQQI RLQAEAFQAR LKSWFEPLVE DMQRQWAGLV EKVQAAVGTS AAPVPSDNH |
Tag | Tag free |
Predicted MW | 34.2 kDa |
Concentration | >50 ug/mL as determined by Bradford protein assay method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 500mM NaCl, 10% Glycerol |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000032 |
Locus ID | 348 |
UniProt ID | P02649, A0A0S2Z3D5 |
Cytogenetics | 19q13.32 |
Synonyms | AD2; APO-E; ApoE4; LDLCQ5; LPG |
Summary | The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016] |
Protein Families | Adult stem cells, Druggable Genome, Secreted Protein, Stem cell - Pluripotency |
Protein Pathways | Alzheimer's disease |
Documents
FAQs |
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Resources
Recombinant Protein Resources |
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