Caspase 2 (CASP2) (NM_032982) Human Recombinant Protein

CAT#: TP760618

Purified recombinant protein of Human caspase 2, apoptosis-related cysteine peptidase (CASP2), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length CASP2
• Tag: N-His
• Predicted MW: 50.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris,8M Urea,pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_116764
• Locus ID: 835
• UniProt ID: P42575, A0A0S2Z3H1
• Cytogenetics: 7q34
• Refseq Size: 4242
• Refseq ORF: 1356
• Synonyms: CASP-2; ICH1; NEDD-2; NEDD2; PPP1R57
• Summary: 'This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]'
• Protein Families: Druggable Genome, Protease