CBARA1 (MICU1) (NM_006077) Human Recombinant Protein
CAT#: TP760929
Purified recombinant protein of Human calcium binding atopy-related autoantigen 1 (CBARA1), nuclear gene encoding mitochondrial protein, transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Other products for "MICU1"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length CBARA1
|
Tag | N-His |
Predicted MW | 54.4 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_006068 |
Locus ID | 10367 |
UniProt ID | Q9BPX6 |
Cytogenetics | 10q22.1 |
Refseq Size | 2506 |
Refseq ORF | 2151 |
Synonyms | ara CALC; CALC; CBARA1; EFHA3; MPXPS |
Summary | This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013] |
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