LKB1 (STK11) (NM_000455) Human Recombinant Protein

CAT#: TP761326

Purified recombinant protein of Human serine/threonine kinase 11 (STK11), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length STK11
Tag N-GST and C-His
Predicted MW 74.5 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000446
Locus ID 6794
UniProt ID Q15831, A0A0S2Z4D1
Cytogenetics 19p13.3
Refseq Size 3286
Refseq ORF 1299
Synonyms hLKB1; LKB1; PJS
Summary 'This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]'
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Adipocytokine signaling pathway, mTOR signaling pathway

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