CMG1 (IFT74) (NM_001099222) Human Recombinant Protein

CAT#: TP761450

Purified recombinant protein of Human intraflagellar transport 74 homolog (Chlamydomonas) (IFT74), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding human full-length IFT74
• Tag: N-His
• Predicted MW: 69.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1% Sarkosyl.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001092692
• Locus ID: 80173
• UniProt ID: Q96LB3
• Cytogenetics: 9p21.2
• Refseq Size: 2183
• Refseq ORF: 1800
• Synonyms: BBS20; CCDC2; CMG-1; CMG1
• Summary: This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome. [provided by RefSeq, Mar 2017]