Endothelin 3 (EDN3) (NM_000114) Human Recombinant Protein
CAT#: TP761588
Purified recombinant protein of Human endothelin 3 (EDN3), transcript variant 1, full length, with N-terminal GST and C-terminal HIS tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length EDN3
|
Tag | N-GST and C-His |
Predicted MW | 50.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0,150mM NaCl,10% glycerol,1%Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000105 |
Locus ID | 1908 |
Cytogenetics | 20q13.32 |
Refseq Size | 2438 |
Refseq ORF | 714 |
Synonyms | ET-3; ET3; HSCR4; PPET3; WS4B |
Summary | 'The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]' |
Protein Families | Druggable Genome, Secreted Protein |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400036 | EDN3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC404139 | EDN3 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY400036 | Transient overexpression lysate of endothelin 3 (EDN3), transcript variant 1 |
USD 396.00 |
|
LY404139 | Transient overexpression lysate of endothelin 3 (EDN3), transcript variant 4 |
USD 396.00 |
|
TP760408 | Purified recombinant protein of Human endothelin 3 (EDN3), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
USD 215.00 |
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