Artemin (ARTN) (NM_057090) Human Recombinant Protein
CAT#: TP761651
Purified recombinant protein of Human artemin (ARTN), transcript variant 4, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length ARTN
|
Tag | N-His |
Predicted MW | 18.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0,8M Urea. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_476431 |
Locus ID | 9048 |
UniProt ID | Q5T4W7 |
Cytogenetics | 1p34.1 |
Refseq Size | 1162 |
Refseq ORF | 684 |
Synonyms | ART; ENOVIN; EVN; NBN |
Summary | This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma. [provided by RefSeq, Aug 2016] |
Protein Families | Druggable Genome, Secreted Protein |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC409292 | ARTN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC409293 | ARTN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC427855 | ARTN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY409292 | Transient overexpression lysate of artemin (ARTN), transcript variant 4 |
USD 396.00 |
|
LY409293 | Transient overexpression lysate of artemin (ARTN), transcript variant 2 |
USD 396.00 |
|
LY427855 | Transient overexpression lysate of artemin (ARTN), transcript variant 5 |
USD 396.00 |
|
TP723024 | Purified recombinant protein of Human artemin (ARTN), transcript variant 4. |
USD 240.00 |
|
TP761756 | Purified recombinant protein of Human artemin (ARTN), transcript variant 5, full length, with N-terminal His tag, expressed in E. coli, 50ug |
USD 215.00 |
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