Claudin 15 (CLDN15) (NM_138429) Human Recombinant Protein

CAT#: TP761793

Purified recombinant protein of Human claudin 15 (CLDN15), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Tag: N-GST and C-His
• Predicted MW: 52.2 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0,8M Urea.

Reference Data

• RefSeq: NP_612438
• Locus ID: 24146
• Cytogenetics: 7q22.1
• Refseq Size: 1200
• Refseq ORF: 384
• Synonyms: claudin 15; FLJ42715; MGC19536
• Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]
• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction