DC2L1 (DYNC2LI1) (NM_015522) Human Recombinant Protein
CAT#: TP761800
Purified recombinant protein of Human dynein, cytoplasmic 2, light intermediate chain 1 (DYNC2LI1), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length DYNC2LI1
|
Tag | N-GST and C-His |
Predicted MW | 50.3 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0,8M Urea. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_056337 |
Locus ID | 51626 |
UniProt ID | Q8TCX1 |
Cytogenetics | 2p21 |
Refseq Size | 1157 |
Refseq ORF | 603 |
Synonyms | CGI-60; D2LIC; LIC3 |
Summary | This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017] |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC414493 | DYNC2LI1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC422811 | DYNC2LI1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC425327 | DYNC2LI1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY414493 | Transient overexpression lysate of dynein, cytoplasmic 2, light intermediate chain 1 (DYNC2LI1), transcript variant 2 |
USD 396.00 |
|
LY422811 | Transient overexpression lysate of dynein, cytoplasmic 2, light intermediate chain 1 (DYNC2LI1), transcript variant 3 |
USD 396.00 |
|
LY425327 | Transient overexpression lysate of dynein, cytoplasmic 2, light intermediate chain 1 (DYNC2LI1), transcript variant 3 |
USD 396.00 |
{0} Product Review(s)
Be the first one to submit a review