PNPLA1 (NM_173676) Human Recombinant Protein
CAT#: TP761955
Purified recombinant protein of Human patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 1,full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding full-length of PNPLA1
|
Tag | N-GST and C-His |
Predicted MW | 75.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_775947 |
Locus ID | 285848 |
UniProt ID | Q8N8W4 |
Cytogenetics | 6p21.31 |
Refseq Size | 2367 |
Refseq ORF | 1311 |
Synonyms | ARCI10; dJ50J22.1 |
Summary | The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012] |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC406553 | PNPLA1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC428981 | PNPLA1 HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY406553 | Transient overexpression lysate of patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 1 |
USD 605.00 |
|
LY428981 | Transient overexpression lysate of patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 3 |
USD 396.00 |
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