VPS35 (NM_018206) Human Recombinant Protein

CAT#: TP761987

Purified recombinant protein of Human vacuolar protein sorting 35 homolog (S. cerevisiae) (VPS35),Ser437-Asp551, with N-terminal His-ABP tag, expressed in E. coli, 50ug


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USD 215.00

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Size
    • 50 ug

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region(Ser437-Asp551)of VPS35
Tag N-His-ABP
Predicted MW 28.1 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_060676
Locus ID 55737
UniProt ID Q96QK1
Cytogenetics 16q11.2
Refseq Size 3298
Refseq ORF 2388
Synonyms MEM3; PARK17
Summary This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]

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