TET2 (NM_001127208) Human Recombinant Protein

CAT#: TP762045

Purified recombinant protein of Human tet oncogene family member 2 (TET2), transcript variant 1,Lys423-Gln740, with N-terminal His tag, expressed in E. coli, 50ug

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Lys423-Gln740) of TET2
• Tag: N-His
• Predicted MW: 36.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_001120680
• Locus ID: 54790
• UniProt ID: Q6N021, A0A158SIU0
• Cytogenetics: 4q24
• Refseq ORF: 6006
• Synonyms: KIAA1546; MDS
• Summary: The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]