VAP1 (AOC3) (NM_003734) Human Recombinant Protein

CAT#: TP762187

Purified recombinant protein of Human amine oxidase, copper containing 3 (vascular adhesion protein 1) (AOC3), Gly27-Pro256, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein AOC3 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Gly27-Pro256) of AOC3
• Tag: N-His
• Predicted MW: 25.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_003725
• Locus ID: 8639
• UniProt ID: Q16853, Q9UEU7
• Cytogenetics: 17q21.31
• Refseq Size: 4040
• Refseq ORF: 2289
• Synonyms: HPAO; SSAO; VAP-1; VAP1
• Summary: This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
• Protein Families: Transmembrane
• Protein Pathways: beta-Alanine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Phenylalanine metabolism, Tyrosine metabolism