Factor V (F5) (NM_000130) Human Recombinant Protein

CAT#: TP762253

Purified recombinant protein of Human coagulation factor V (proaccelerin, labile factor) (F5), Pro302-Ile585, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein F5 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Pro302-Ile585) of F5
• Tag: N-His
• Predicted MW: 33.3 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_000121
• Locus ID: 2153
• UniProt ID: P12259
• Cytogenetics: 1q24.2
• Refseq Size: 6914
• Refseq ORF: 6672
• Synonyms: FVL; PCCF; RPRGL1; THPH2
• Summary: 'This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]'
• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades