GRK4 (NM_182982) Human Recombinant Protein

CAT#: TP762271

Purified recombinant protein of Human G protein-coupled receptor kinase 4 (GRK4), transcript variant 1, Met1-Arg245, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein GRK4 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Met1-Arg245) of GRK4
• Tag: N-His
• Predicted MW: 28.4 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, 8M Urea, pH8.0.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_892027
• Locus ID: 2868
• UniProt ID: P32298
• Cytogenetics: 4p16.3
• Refseq Size: 2321
• Refseq ORF: 1734
• Synonyms: GPRK2L; GPRK4; GRK4a; IT11
• Summary: 'This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]'
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Chemokine signaling pathway, Endocytosis