Tyrosinase (TYR) (NM_000372) Human Recombinant Protein
CAT#: TP762332
Purified recombinant protein of Human tyrosinase (oculocutaneous albinism IA) (TYR), His19-Phe320, with N-terminal His tag, expressed in E.coli, 50ug
Other products for "TYR"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(His19-Phe320) of TYR
|
Tag | N-His |
Predicted MW | 34.6 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 8M Urea |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000363 |
Locus ID | 7299 |
UniProt ID | P14679, L8B082 |
Cytogenetics | 11q14.3 |
Refseq Size | 1964 |
Refseq ORF | 1587 |
Synonyms | ATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3 |
Summary | 'The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]' |
Protein Families | Transmembrane |
Protein Pathways | Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism |
Documents
FAQs |
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Resources
Recombinant Protein Resources |
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