TTF1 (NKX2-1) (NM_003317) Human Recombinant Protein

CAT#: TP762355

Purified recombinant protein of Human NK2 homeobox 1 (NKX2-1), transcript variant 2, Gly89-Pro123-GGGGS-Leu156-His193, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein TTF1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region(Gly89-Pro123-GGGGS-Leu156-His193) of TTF1
• Tag: N-His
• Predicted MW: 8.8 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_003308
• Locus ID: 7080
• UniProt ID: P43699
• Cytogenetics: 14q13.3
• Refseq Size: 2352
• Refseq ORF: 1113
• Synonyms: BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1
• Summary: 'This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]'
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors