GTF3A (NM_002097) Human Recombinant Protein

CAT#: TP762379

Purified recombinant protein of Human general transcription factor IIIA (GTF3A), full length, with N-terminal GST tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein GTF3A was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the full-length of GTF3A
• Tag: N-GFP
• Predicted MW: 69.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002088
• Locus ID: 2971
• UniProt ID: Q92664
• Cytogenetics: 13q12.2
• Refseq Size: 1404
• Refseq ORF: 1095
• Synonyms: AP2; TFIIIA
• Summary: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
• Protein Families: Transcription Factors