TMEM16A (ANO1) (NM_018043) Human Recombinant Protein

CAT#: TP762380

Purified recombinant protein of Human anoctamin 1, calcium activated chloride channel (ANO1), transcript variant 1, Met1-Ala333, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein ANO1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region (Met1-Ala333) of ANO1
• Tag: N-His
• Predicted MW: 38.5 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_060513
• Locus ID: 55107
• UniProt ID: Q5XXA6, Q9NW72
• Cytogenetics: 11q13.3
• Refseq ORF: 2958
• Synonyms: DOG1; ORAOV2; TAOS2; TMEM16A
• Summary: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. [UniProtKB/Swiss-Prot Function]
• Protein Families: Transmembrane