HMG1 (HMGB1) (NM_002128) Human Recombinant Protein

CAT#: TP762387

Purified recombinant protein of Human high mobility group box 1 (HMGB1), full length, with N-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein HMGB1 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the full length of HMGB1
• Tag: N-His
• Predicted MW: 24.9 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_002119
• Locus ID: 3146
• UniProt ID: P09429, A0A024RDR0
• Cytogenetics: 13q12.3
• Refseq Size: 3428
• Refseq ORF: 645
• Synonyms: HMG-1; HMG1; HMG3; SBP-1
• Summary: 'This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]'
• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors
• Protein Pathways: Base excision repair