MYBPC3 (NM_000256) Human Recombinant Protein
CAT#: TP762402
Purified recombinant protein of Human myosin binding protein C, cardiac (MYBPC3), Asp151-Glu258, with N-terminal His tag, expressed in E.coli, 50ug
Other products for "MYBPC3"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Asp151-Glu258) of MYBPC3
|
Tag | N-His |
Predicted MW | 12.0 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 8M Urea |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_000247 |
Locus ID | 4607 |
Cytogenetics | 11p11.2 |
Refseq Size | 4200 |
Refseq ORF | 3822 |
Synonyms | CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C |
Summary | 'MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]' |
Protein Families | Druggable Genome |
Protein Pathways | Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
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