RSPO1 (NM_001038633) Human Recombinant Protein
CAT#: TP762458
Purified recombinant protein of Human R-spondin homolog (Xenopus laevis) (RSPO1), Ser21-End, with N-terminal His tag, expressed in E.coli, 50ug
Other products for "RSPO1"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Ser21-End) of RSPO1
|
Tag | N-His |
Predicted MW | 26.8 kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50mM Tris, pH8.0, 8M Urea |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001033722 |
Locus ID | 284654 |
UniProt ID | Q2MKA7 |
Cytogenetics | 1p34.3 |
Refseq Size | 2995 |
Refseq ORF | 789 |
Synonyms | CRISTIN3; RSPO |
Summary | This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Protein Families | Secreted Protein |
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