Ribonuclease H2, subunit A (RNASEH2A) (NM_006397) Human Recombinant Protein
CAT#: TP762504
Purified recombinant protein of Human ribonuclease H2, subunit A (RNASEH2A), full length, with N-terminal His tag, expressed in E.coli, 50ug
Other products for "RNASEH2A"
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region full length of RNASEH2A
|
Tag | N-His |
Predicted MW | 35.7kDa |
Concentration | >50 ug/mL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_006388 |
Locus ID | 10535 |
UniProt ID | O75792 |
Cytogenetics | 19p13.13 |
Refseq Size | 1148 |
Refseq ORF | 897 |
Synonyms | AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8 |
Summary | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009] |
Protein Pathways | DNA replication |
Documents
FAQs |
SDS |
Resources
Recombinant Protein Resources |
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