Calpain 3 (CAPN3) (NM_173089) Human Recombinant Protein

CAT#: TP762509

Purified recombinant protein of Human calpain 3, (p94) (CAPN3), transcript variant 5, full length, 50ug

Product Images

Coomassie blue staining of purified CAPN3 protein (Cat #TP762509). The protein was produced from E.coli.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of CAPN3
• Tag: N-His
• Predicted MW: 18.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_775112
• Locus ID: 825
• UniProt ID: P20807
• Cytogenetics: 15q15.1
• Refseq Size: 1291
• Refseq ORF: 468
• Synonyms: CANP3; CANPL3; LGMD2; LGMD2A; LGMDD4; LGMDR1; nCL-1; p94
• Summary: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Protease