CILK1 (NM_016513) Human Recombinant Protein

CAT#: TP762614

Purified recombinant protein of Human intestinal cell (MAK-like) kinase (ICK), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein ICK was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of ICK
• Tag: N-GST and C-HIS
• Predicted MW: 71.2 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_057597
• Locus ID: 22858
• UniProt ID: Q9UPZ9, A0A024RD59, B3KQG4
• Cytogenetics: 6p12.1
• Refseq Size: 6228
• Refseq ORF: 1896
• Synonyms: ECO; EJM10; hICK; ICK; LCK2; MRK
• Summary: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Protein Kinase