RDH12 (NM_152443) Human Recombinant Protein

CAT#: TP762691

Purified recombinant protein of Human retinol dehydrogenase 12 (all-trans/9-cis/11-cis) (RDH12), full length, with N-GST and C-His tag, expressed in E.coli, 50ug

Product Images

Purified recombinant protein RDH12 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence encoding the region full length of RDH12
• Tag: N-GST and C-HIS
• Predicted MW: 63.1 kDa
• Concentration: >50 ug/mL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 50mM Tris, pH8.0, 8M Urea
• Storage: Store at -80°C after receiving vials.
• Stability: Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.

Reference Data

• RefSeq: NP_689656
• Locus ID: 145226
• UniProt ID: Q96NR8, A0A0S2Z613
• Cytogenetics: 14q24.1
• Refseq Size: 1934
• Refseq ORF: 948
• Synonyms: LCA13; RP53; SDR7C2
• Summary: The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 13 and Retinitis Pigmentosa 53. [provided by RefSeq, Sep 2015]
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Retinol metabolism