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Target Symbol
- VSNL1 (91)
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- GLI1 (46)
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- BNIP1 (14)
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Applications
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Knockout (KO) Validation
Families
- Druggable Genome (4678)
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- Secreted Protein (329)
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- Adult stem cells (172)
- Cancer stem cells (114)
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- Phosphatase (93)
- Stem cell relevant signaling - DSL/Notch pathway (75)
- Stem cell relevant signaling - JAK/STAT signaling pathway (63)
- Ion Channels: Other (45)
- Induced pluripotent stem cells (39)
- GPCR (36)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (33)
- P450 (9)
- Stem cell relevant signaling - Wnt Signaling pathway (8)
- Ion Channels: Cys-loop Receptors (6)
- Ion Channels: Potassium (5)
- Ion Channels: Transient receptor potential (2)
Pathways
- Metabolic pathways (779)
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- MAPK signaling pathway (471)
- Focal adhesion (398)
- Colorectal cancer (331)
- Neurotrophin signaling pathway (320)
- Prostate cancer (310)
- ErbB signaling pathway (306)
- T cell receptor signaling pathway (271)
- Regulation of actin cytoskeleton (265)
- Insulin signaling pathway (250)
- B cell receptor signaling pathway (249)
- Melanoma (241)
- Renal cell carcinoma (240)
- Glioma (239)
- Endometrial cancer (235)
- Pancreatic cancer (233)
- Non-small cell lung cancer (230)
- GnRH signaling pathway (219)
- Chronic myeloid leukemia (203)
- Toll-like receptor signaling pathway (201)
- Acute myeloid leukemia (199)
- Progesterone-mediated oocyte maturation (197)
- Bladder cancer (190)
- Chemokine signaling pathway (182)
- Purine metabolism (182)
- Wnt signaling pathway (182)
- Cell cycle (170)
- Endocytosis (169)
- Fc epsilon RI signaling pathway (159)
- VEGF signaling pathway (157)
- Gap junction (153)
- Epithelial cell signaling in Helicobacter pylori infection (152)
- Adherens junction (148)
- Pyrimidine metabolism (148)
- Leukocyte transendothelial migration (137)
- Long-term potentiation (135)
- Natural killer cell mediated cytotoxicity (135)
- Small cell lung cancer (129)
- Alzheimer's disease (125)
- Oocyte meiosis (123)
- Thyroid cancer (123)
- Tight junction (123)
- mTOR signaling pathway (122)
- Melanogenesis (121)
- Axon guidance (120)
- Long-term depression (119)
- Hedgehog signaling pathway (112)
- Calcium signaling pathway (111)
- Basal cell carcinoma (110)
- Ubiquitin mediated proteolysis (108)
- Cell adhesion molecules (CAMs) (103)
- Apoptosis (100)
- Adipocytokine signaling pathway (98)
- Fc gamma R-mediated phagocytosis (98)
- Huntington's disease (96)
- Cytokine-cytokine receptor interaction (95)
- Arginine and proline metabolism (94)
- Jak-STAT signaling pathway (94)
- Dorso-ventral axis formation (93)
- Nucleotide excision repair (93)
- TGF-beta signaling pathway (92)
- Type II diabetes mellitus (84)
- p53 signaling pathway (84)
- RNA degradation (83)
- Glycolysis / Gluconeogenesis (78)
- Vascular smooth muscle contraction (77)
- Amyotrophic lateral sclerosis (ALS) (75)
- Parkinson's disease (74)
- Prion diseases (70)
- Oxidative phosphorylation (69)
- Alanine (66)
- aspartate and glutamate metabolism (66)
- Notch signaling pathway (65)
- Spliceosome (63)
- Valine (62)
- leucine and isoleucine degradation (62)
- Hypertrophic cardiomyopathy (HCM) (61)
- NOD-like receptor signaling pathway (58)
- ABC transporters (56)
- Dilated cardiomyopathy (56)
- Mismatch repair (56)
- Tyrosine metabolism (52)
- DNA replication (51)
- Glutathione metabolism (48)
- Inositol phosphate metabolism (48)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (47)
- PPAR signaling pathway (47)
- Lysine degradation (46)
- Proteasome (46)
- Circadian rhythm - mammal (45)
- Maturity onset diabetes of the young (44)
- Neuroactive ligand-receptor interaction (44)
- Phosphatidylinositol signaling system (43)
- Propanoate metabolism (43)
- Fatty acid metabolism (42)
- Glycine (41)
- One carbon pool by folate (41)
- Pathogenic Escherichia coli infection (41)
- serine and threonine metabolism (41)
- RIG-I-like receptor signaling pathway (40)
- Butanoate metabolism (38)
- Cardiac muscle contraction (38)
- Base excision repair (36)
- Citrate cycle (TCA cycle) (34)
- beta-Alanine metabolism (34)
- Arachidonic acid metabolism (32)
- SNARE interactions in vesicular transport (32)
- Vibrio cholerae infection (32)
- Porphyrin and chlorophyll metabolism (31)
- Pyruvate metabolism (31)
- Pentose phosphate pathway (30)
- RNA polymerase (30)
- Ribosome (30)
- Tryptophan metabolism (30)
- Antigen processing and presentation (28)
- Histidine metabolism (28)
- Complement and coagulation cascades (26)
- Methane metabolism (26)
- Cytosolic DNA-sensing pathway (24)
- Drug metabolism - cytochrome P450 (24)
- Glycerolipid metabolism (24)
- Lysosome (24)
- Primary immunodeficiency (24)
- Starch and sucrose metabolism (24)
- ECM-receptor interaction (23)
- Hematopoietic cell lineage (23)
- Viral myocarditis (23)
- Drug metabolism - other enzymes (22)
- Fructose and mannose metabolism (22)
- Metabolism of xenobiotics by cytochrome P450 (22)
- Amino sugar and nucleotide sugar metabolism (20)
- Selenoamino acid metabolism (20)
- Galactose metabolism (19)
- N-Glycan biosynthesis (18)
- Sulfur metabolism (18)
- Basal transcription factors (17)
- Cysteine and methionine metabolism (17)
- Type I diabetes mellitus (17)
- Nicotinate and nicotinamide metabolism (16)
- Olfactory transduction (16)
- Primary bile acid biosynthesis (16)
- Fatty acid elongation in mitochondria (15)
- Glyoxylate and dicarboxylate metabolism (15)
- Retinol metabolism (15)
- Ascorbate and aldarate metabolism (14)
- Ether lipid metabolism (14)
- Nitrogen metabolism (13)
- Phenylalanine metabolism (13)
- Other glycan degradation (12)
- Regulation of autophagy (12)
- Sphingolipid metabolism (12)
- Androgen and estrogen metabolism (11)
- Homologous recombination (10)
- Renin-angiotensin system (10)
- Aminoacyl-tRNA biosynthesis (9)
- Glycerophospholipid metabolism (9)
- Terpenoid backbone biosynthesis (9)
- Synthesis and degradation of ketone bodies (8)
- Riboflavin metabolism (7)
- Allograft rejection (6)
- Autoimmune thyroid disease (6)
- Graft-versus-host disease (6)
- Non-homologous end-joining (6)
- Folate biosynthesis (5)
- Limonene and pinene degradation (5)
- Thiamine metabolism (5)
- Cyanoamino acid metabolism (4)
- O-Glycan biosynthesis (4)
- Pantothenate and CoA biosynthesis (4)
- Systemic lupus erythematosus (3)
- Biosynthesis of unsaturated fatty acids (2)
- D-Glutamine and D-glutamate metabolism (2)
- Glycosaminoglycan degradation (2)
- Glycosphingolipid biosynthesis - ganglio series (2)
- Keratan sulfate biosynthesis (2)
- Linoleic acid metabolism (2)
- Pentose and glucuronate interconversions (2)
- Taste transduction (2)
- Vitamin B6 metabolism (2)
- alpha-Linolenic acid metabolism (2)
- Caffeine metabolism (1)
- Taurine and hypotaurine metabolism (1)