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Category
Target Symbol
- ALK (50)
- EGFR (40)
- MAP2K1 (24)
- ERBB2 (22)
- BRAF (19)
- RPS6KA2 (17)
- ERBB3 (14)
- TRIM24 (14)
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- MAPK1 (10)
- MAPK13 (10)
- MAPK7 (10)
- MAPK9 (10)
- MTOR (10)
- MAST2 (9)
- PDGFRB (9)
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- MET (8)
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- CDKL2 (7)
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- CDC42BPA (5)
- NTRK3 (5)
- PAK4 (5)
- RPS6KB1 (5)
- TRIM28 (5)
- TYRO3 (5)
- CSNK1E (4)
- ERBB4 (4)
- FGFR1 (4)
- IGF1R (4)
- JAK2 (4)
- MAP2K2 (4)
- MOK (4)
- PDIK1L (4)
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- STK39 (4)
- TP53RK (4)
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- VRK1 (3)
- CDK15 (2)
- CDK20 (2)
- CDK5 (2)
- DYRK2 (2)
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- DAPK2 (1)
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- MAPK11 (1)
Applications
Knockout (KO) Validation
Pathways
- MAPK signaling pathway (234)
- Pathways in cancer (233)
- ErbB signaling pathway (217)
- Focal adhesion (203)
- Prostate cancer (194)
- Colorectal cancer (170)
- Glioma (169)
- Melanoma (162)
- Pancreatic cancer (159)
- Neurotrophin signaling pathway (154)
- Regulation of actin cytoskeleton (151)
- Endometrial cancer (147)
- Non-small cell lung cancer (147)
- GnRH signaling pathway (134)
- Progesterone-mediated oocyte maturation (133)
- Bladder cancer (130)
- Gap junction (118)
- Insulin signaling pathway (114)
- Calcium signaling pathway (110)
- Fc epsilon RI signaling pathway (106)
- Acute myeloid leukemia (102)
- Toll-like receptor signaling pathway (101)
- Endocytosis (98)
- Renal cell carcinoma (98)
- T cell receptor signaling pathway (94)
- Adherens junction (93)
- Long-term potentiation (91)
- mTOR signaling pathway (89)
- Cytokine-cytokine receptor interaction (88)
- Chemokine signaling pathway (87)
- Chronic myeloid leukemia (87)
- VEGF signaling pathway (81)
- Epithelial cell signaling in Helicobacter pylori infection (77)
- Dorso-ventral axis formation (76)
- Long-term depression (75)
- Vascular smooth muscle contraction (75)
- Oocyte meiosis (71)
- Fc gamma R-mediated phagocytosis (67)
- B cell receptor signaling pathway (66)
- Natural killer cell mediated cytotoxicity (65)
- Thyroid cancer (62)
- Adipocytokine signaling pathway (54)
- Melanogenesis (49)
- Type II diabetes mellitus (42)
- Prion diseases (40)
- NOD-like receptor signaling pathway (39)
- Axon guidance (36)
- Small cell lung cancer (28)
- TGF-beta signaling pathway (28)
- RIG-I-like receptor signaling pathway (27)
- Tight junction (27)
- Wnt signaling pathway (27)
- Apoptosis (24)
- Jak-STAT signaling pathway (24)
- Hedgehog signaling pathway (20)
- Leukocyte transendothelial migration (20)
- Amyotrophic lateral sclerosis (ALS) (19)
- Olfactory transduction (15)
- Alzheimer's disease (14)
- Cell cycle (10)
- p53 signaling pathway (7)
- Primary immunodeficiency (6)
- Circadian rhythm - mammal (4)
- Hematopoietic cell lineage (2)
- Purine metabolism (2)
- Regulation of autophagy (2)