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Category
Target Symbol
- MAP2K3 (13)
- MAP2K1 (12)
- ACAT2 (5)
- RAB21 (4)
- ACAA2 (3)
- CHEK2 (3)
- CTNNB1 (3)
- PIK3R5 (3)
- PRKCE (3)
- PSMA2 (3)
- RAB30 (3)
- SAMHD1 (3)
- SERPINB1 (3)
- BSG (2)
- CBWD1 (2)
- EPHX1 (2)
- FOXA1 (2)
- MAPK13 (2)
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- PACSIN3 (2)
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- PPP5C (2)
- SNX9 (2)
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- TUBAL3 (2)
- XPNPEP3 (2)
- AFP (1)
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- APMAP (1)
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- LTA4H (1)
- MAP2K4 (1)
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- OSBPL11 (1)
- PCNA (1)
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- PNMT (1)
- PPP1R15A (1)
- PPT1 (1)
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- PRKD2 (1)
- PSMA4 (1)
- PSMA6 (1)
- PSMB7 (1)
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- SESTD1 (1)
- SETD7 (1)
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- SNTA1 (1)
- STK3 (1)
- SULT1C2 (1)
Clonalities
Knockout (KO) Validation
Families
- Druggable Genome (125)
- Protein Kinase (39)
- Transcription Factors (25)
- Protease (16)
- Transmembrane (13)
- Stem cell - Pluripotency (10)
- ES Cell Differentiation/IPS (8)
- Secreted Protein (5)
- Adult stem cells (1)
- Ion Channels: Potassium (1)
- Phosphatase (1)
- Stem cell relevant signaling - DSL/Notch pathway (1)
Pathways
- Fc epsilon RI signaling pathway (35)
- MAPK signaling pathway (33)
- Toll-like receptor signaling pathway (31)
- GnRH signaling pathway (29)
- Pathways in cancer (22)
- Metabolic pathways (21)
- Focal adhesion (20)
- Progesterone-mediated oocyte maturation (20)
- Prostate cancer (20)
- Endometrial cancer (19)
- Fc gamma R-mediated phagocytosis (19)
- T cell receptor signaling pathway (19)
- VEGF signaling pathway (19)
- Colorectal cancer (18)
- Neurotrophin signaling pathway (18)
- Chronic myeloid leukemia (17)
- ErbB signaling pathway (17)
- Gap junction (17)
- Renal cell carcinoma (17)
- Acute myeloid leukemia (16)
- B cell receptor signaling pathway (16)
- Chemokine signaling pathway (16)
- Glioma (16)
- Insulin signaling pathway (16)
- Melanogenesis (16)
- Melanoma (16)
- Natural killer cell mediated cytotoxicity (16)
- Non-small cell lung cancer (16)
- Pancreatic cancer (16)
- Regulation of actin cytoskeleton (16)
- Thyroid cancer (16)
- Amyotrophic lateral sclerosis (ALS) (15)
- Vascular smooth muscle contraction (15)
- Bladder cancer (14)
- Long-term depression (13)
- Long-term potentiation (13)
- Oocyte meiosis (13)
- Dorso-ventral axis formation (12)
- Prion diseases (12)
- Valine (11)
- leucine and isoleucine degradation (11)
- Fatty acid metabolism (10)
- Leukocyte transendothelial migration (8)
- Pathogenic Escherichia coli infection (8)
- Lysine degradation (7)
- Propanoate metabolism (7)
- Tight junction (7)
- Butanoate metabolism (6)
- Cell cycle (6)
- Proteasome (6)
- Pyruvate metabolism (6)
- Tryptophan metabolism (6)
- Type II diabetes mellitus (6)
- Synthesis and degradation of ketone bodies (5)
- Terpenoid backbone biosynthesis (5)
- Wnt signaling pathway (5)
- Fatty acid elongation in mitochondria (4)
- Phosphatidylinositol signaling system (4)
- mTOR signaling pathway (4)
- Adherens junction (3)
- Apoptosis (3)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (3)
- Basal cell carcinoma (3)
- Epithelial cell signaling in Helicobacter pylori infection (3)
- Jak-STAT signaling pathway (3)
- NOD-like receptor signaling pathway (3)
- Nucleotide excision repair (3)
- Small cell lung cancer (3)
- beta-Alanine metabolism (3)
- p53 signaling pathway (3)
- Amino sugar and nucleotide sugar metabolism (2)
- Arachidonic acid metabolism (2)
- Arginine and proline metabolism (2)
- Base excision repair (2)
- Cysteine and methionine metabolism (2)
- Endocytosis (2)
- Glutathione metabolism (2)
- Glycerolipid metabolism (2)
- Glycolysis / Gluconeogenesis (2)
- Huntington's disease (2)
- Metabolism of xenobiotics by cytochrome P450 (2)
- RIG-I-like receptor signaling pathway (2)
- RNA degradation (2)
- Ubiquitin mediated proteolysis (2)
- Alzheimer's disease (1)
- Aminoacyl-tRNA biosynthesis (1)
- Antigen processing and presentation (1)
- Ascorbate and aldarate metabolism (1)
- Axon guidance (1)
- Calcium signaling pathway (1)
- Citrate cycle (TCA cycle) (1)
- Complement and coagulation cascades (1)
- Cytokine-cytokine receptor interaction (1)
- DNA replication (1)
- Glycerophospholipid metabolism (1)
- Glycine (1)
- Hematopoietic cell lineage (1)
- Histidine metabolism (1)
- Limonene and pinene degradation (1)
- Linoleic acid metabolism (1)
- Lysosome (1)
- Mismatch repair (1)
- Nitrogen metabolism (1)
- Notch signaling pathway (1)
- Oxidative phosphorylation (1)
- Parkinson's disease (1)
- Pentose phosphate pathway (1)
- Primary immunodeficiency (1)
- Purine metabolism (1)
- Renin-angiotensin system (1)
- Selenoamino acid metabolism (1)
- Spliceosome (1)
- Starch and sucrose metabolism (1)
- Systemic lupus erythematosus (1)
- TGF-beta signaling pathway (1)
- Tyrosine metabolism (1)
- Vibrio cholerae infection (1)
- serine and threonine metabolism (1)