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Target Symbol
- MAP2K1 (23)
- MAP2K3 (20)
- PDCD1 (20)
- UBE2G2 (19)
- ERBB2 (15)
- CD163 (12)
- MMP13 (12)
- RAB37 (12)
- ERG (11)
- SNX9 (11)
- KLK8 (10)
- LGR5 (10)
- TLE1 (10)
- TUBB2B (10)
- CATIP (9)
- CTNNB1 (9)
- SNAP25 (9)
- CDK2 (8)
- LIPG (8)
- PSMD2 (8)
- SYP (8)
- APP (7)
- BECN1 (7)
- FGFR2 (7)
- GAS7 (7)
- IDS (7)
- PARVA (7)
- RHOJ (7)
- TUBB1 (7)
- B3GNT2 (6)
- BTK (6)
- CYP1A2 (6)
- FERMT2 (6)
- GPHN (6)
- LIMK1 (6)
- MCL1 (6)
- MDM4 (6)
- PIK3CG (6)
- PNMT (6)
- PTPN1 (6)
- SCAMP2 (6)
- SIVA1 (6)
- TRIM9 (6)
- UPRT (6)
- VIM (6)
- ZSCAN18 (6)
- AP2M1 (5)
- BID (5)
- CD80 (5)
- CPA1 (5)
- EPCAM (5)
- ERCC1 (5)
- MAP2K2 (5)
- MAPRE2 (5)
- MSI1 (5)
- MYC (5)
- PYCR2 (5)
- SOCS3 (5)
- SPG7 (5)
- TGFB1 (5)
- ADH1B (4)
- AFP (4)
- APEX1 (4)
- ATG3 (4)
- BEST3 (4)
- C1ORF50 (4)
- CA12 (4)
- CMPK1 (4)
- DCK (4)
- DEF6 (4)
- DTNA (4)
- ERCC4 (4)
- FBXO21 (4)
- FOXI1 (4)
- HOXC11 (4)
- IRF3 (4)
- KRT19 (4)
- MCAT (4)
- MEF2C (4)
- MYD88 (4)
- NDEL1 (4)
- NDOR1 (4)
- PANK2 (4)
- PGAM2 (4)
- PGR (4)
- PIK3R5 (4)
- PIM2 (4)
- PKLR (4)
- PKMYT1 (4)
- PYCR3 (4)
- RAB30 (4)
- RBP1 (4)
- TFR2 (4)
- TUBA8 (4)
- TUBB2A (4)
- TUBB4A (4)
- ACTN1 (3)
- ALDH1L1 (3)
- ATP6V1F (3)
- ATRIP (3)
Antibody Hosts
Knockout (KO) Validation
Families
- Druggable Genome (746)
- Transmembrane (228)
- Transcription Factors (142)
- Protein Kinase (124)
- Secreted Protein (97)
- ES Cell Differentiation/IPS (79)
- Protease (58)
- Stem cell - Pluripotency (32)
- P450 (16)
- Embryonic stem cells (12)
- Phosphatase (12)
- Adult stem cells (10)
- GPCR (10)
- Ion Channels: Other (9)
- Induced pluripotent stem cells (6)
- Stem cell relevant signaling - JAK/STAT signaling pathway (5)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (5)
- Stem cell relevant signaling - Wnt Signaling pathway (5)
- Nuclear Hormone Receptor (4)
- Cancer stem cells (3)
- Stem cell relevant signaling - DSL/Notch pathway (3)
- Ion Channels: Calcium (1)
Pathways
- Metabolic pathways (153)
- Pathways in cancer (113)
- MAPK signaling pathway (95)
- Prostate cancer (84)
- Toll-like receptor signaling pathway (84)
- Focal adhesion (76)
- Fc epsilon RI signaling pathway (74)
- Endometrial cancer (72)
- ErbB signaling pathway (68)
- Regulation of actin cytoskeleton (67)
- Gap junction (65)
- Pancreatic cancer (65)
- Progesterone-mediated oocyte maturation (64)
- T cell receptor signaling pathway (63)
- Colorectal cancer (62)
- Insulin signaling pathway (60)
- Non-small cell lung cancer (58)
- Chronic myeloid leukemia (57)
- GnRH signaling pathway (57)
- Bladder cancer (52)
- Acute myeloid leukemia (51)
- Natural killer cell mediated cytotoxicity (51)
- B cell receptor signaling pathway (49)
- Neurotrophin signaling pathway (49)
- Melanoma (47)
- Renal cell carcinoma (47)
- Oocyte meiosis (46)
- Thyroid cancer (46)
- Fc gamma R-mediated phagocytosis (45)
- Glioma (45)
- Pathogenic Escherichia coli infection (44)
- VEGF signaling pathway (42)
- Chemokine signaling pathway (39)
- Melanogenesis (38)
- Cell adhesion molecules (CAMs) (37)
- Adherens junction (36)
- Cell cycle (32)
- Jak-STAT signaling pathway (32)
- Prion diseases (32)
- Ubiquitin mediated proteolysis (32)
- Vascular smooth muscle contraction (32)
- Amyotrophic lateral sclerosis (ALS) (31)
- Long-term depression (31)
- Long-term potentiation (31)
- Small cell lung cancer (28)
- Apoptosis (26)
- Type II diabetes mellitus (26)
- Dorso-ventral axis formation (24)
- Leukocyte transendothelial migration (24)
- Pyrimidine metabolism (22)
- Wnt signaling pathway (22)
- p53 signaling pathway (22)
- Parkinson's disease (21)
- Calcium signaling pathway (20)
- Alzheimer's disease (18)
- Drug metabolism - cytochrome P450 (18)
- Purine metabolism (18)
- Metabolism of xenobiotics by cytochrome P450 (17)
- Proteasome (16)
- Systemic lupus erythematosus (16)
- Arginine and proline metabolism (15)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (15)
- Cytokine-cytokine receptor interaction (15)
- Glycolysis / Gluconeogenesis (15)
- Lysosome (15)
- Retinol metabolism (15)
- Tight junction (15)
- TGF-beta signaling pathway (14)
- mTOR signaling pathway (14)
- Endocytosis (13)
- Graft-versus-host disease (13)
- Hematopoietic cell lineage (13)
- Tyrosine metabolism (13)
- Glycerolipid metabolism (12)
- Primary immunodeficiency (12)
- RIG-I-like receptor signaling pathway (12)
- Type I diabetes mellitus (12)
- Adipocytokine signaling pathway (11)
- Arachidonic acid metabolism (11)
- Axon guidance (11)
- Basal cell carcinoma (11)
- Huntington's disease (11)
- Hypertrophic cardiomyopathy (HCM) (11)
- Phosphatidylinositol signaling system (11)
- Regulation of autophagy (11)
- Allograft rejection (10)
- Cytosolic DNA-sensing pathway (10)
- Glycosaminoglycan degradation (10)
- Inositol phosphate metabolism (10)
- Nucleotide excision repair (10)
- SNARE interactions in vesicular transport (10)
- Sphingolipid metabolism (10)
- Viral myocarditis (10)
- Epithelial cell signaling in Helicobacter pylori infection (9)
- NOD-like receptor signaling pathway (9)
- Autoimmune thyroid disease (8)
- Dilated cardiomyopathy (8)
- Maturity onset diabetes of the young (8)
- Other glycan degradation (8)
- Caffeine metabolism (7)
- Nitrogen metabolism (7)
- Tryptophan metabolism (7)
- Base excision repair (6)
- Fructose and mannose metabolism (6)
- Glycosphingolipid biosynthesis - lacto and neolacto series (6)
- Keratan sulfate biosynthesis (6)
- Linoleic acid metabolism (6)
- Terpenoid backbone biosynthesis (6)
- Alanine (5)
- Complement and coagulation cascades (5)
- Fatty acid metabolism (5)
- Neuroactive ligand-receptor interaction (5)
- Pantothenate and CoA biosynthesis (5)
- Pyruvate metabolism (5)
- Valine (5)
- Vibrio cholerae infection (5)
- aspartate and glutamate metabolism (5)
- beta-Alanine metabolism (5)
- leucine and isoleucine degradation (5)
- Butanoate metabolism (4)
- Fatty acid biosynthesis (4)
- Glutathione metabolism (4)
- Oxidative phosphorylation (4)
- Propanoate metabolism (4)
- Amino sugar and nucleotide sugar metabolism (3)
- Antigen processing and presentation (3)
- Ascorbate and aldarate metabolism (3)
- Citrate cycle (TCA cycle) (3)
- Cysteine and methionine metabolism (3)
- Drug metabolism - other enzymes (3)
- Galactose metabolism (3)
- Glycosphingolipid biosynthesis - ganglio series (3)
- N-Glycan biosynthesis (3)
- One carbon pool by folate (3)
- Porphyrin and chlorophyll metabolism (3)
- RNA degradation (3)
- RNA polymerase (3)
- Renin-angiotensin system (3)
- Spliceosome (3)
- Asthma (2)
- Circadian rhythm - mammal (2)
- ECM-receptor interaction (2)
- Glycine (2)
- Histidine metabolism (2)
- Phenylalanine metabolism (2)
- Synthesis and degradation of ketone bodies (2)
- Taurine and hypotaurine metabolism (2)
- Vitamin B6 metabolism (2)
- serine and threonine metabolism (2)
- Cardiac muscle contraction (1)
- DNA replication (1)
- Glyoxylate and dicarboxylate metabolism (1)
- Hedgehog signaling pathway (1)
- Homologous recombination (1)
- Lysine degradation (1)
- Mismatch repair (1)
- Nicotinate and nicotinamide metabolism (1)
- Notch signaling pathway (1)
- Pentose phosphate pathway (1)
- Starch and sucrose metabolism (1)
- Steroid biosynthesis (1)