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Target Symbol
- MAP2K1 (102)
- NME1 (72)
- OTC (69)
- MAP2K3 (57)
- ABCB1 (51)
- ERBB2 (51)
- PIK3C2A (42)
- PCNA (39)
- VSNL1 (39)
- CTNNB1 (36)
- SENP2 (36)
- TOP2A (36)
- APP (33)
- JUN (30)
- LTA4H (30)
- NPR3 (30)
- PARVA (30)
- PDE4A (30)
- PFKP (30)
- PIK3CG (30)
- PPP5C (30)
- UBE2G2 (30)
- ABAT (27)
- ACAT2 (27)
- AKR1A1 (27)
- BBOX1 (27)
- BCL2 (27)
- BTK (27)
- GCH1 (27)
- LOX (27)
- LPIN1 (27)
- MCM2 (27)
- MEF2C (27)
- MMP13 (27)
- NCAM1 (27)
- POR (27)
- PTPRE (27)
- RET (27)
- TYMS (27)
- ACAA2 (24)
- AGR2 (24)
- AKT1 (24)
- CRYAB (24)
- DEF6 (24)
- EPN2 (24)
- F13A1 (24)
- FBXO21 (24)
- KRT18 (24)
- MTOR (24)
- PDSS2 (24)
- PRKAR2A (24)
- RAB21 (24)
- RHOJ (24)
- SCFD1 (24)
- SRR (24)
- STAT4 (24)
- SYP (24)
- TLE1 (24)
- TSC22D1 (24)
- TTLL12 (24)
- UNG (24)
- UPRT (24)
- ALDH1L1 (21)
- APMAP (21)
- ARHGAP25 (21)
- BCL10 (21)
- CMPK1 (21)
- DNM1L (21)
- ESR1 (21)
- GADD45G (21)
- GLI1 (21)
- GPR17 (21)
- HADH (21)
- HSPD1 (21)
- ID3 (21)
- KRT16 (21)
- L1CAM (21)
- LPL (21)
- NR3C1 (21)
- NRBP1 (21)
- PIK3R5 (21)
- PIM2 (21)
- PSMB9 (21)
- RFXANK (21)
- RGS16 (21)
- RPA2 (21)
- SNAP25 (21)
- SNX9 (21)
- SQSTM1 (21)
- TBC1D21 (21)
- TLK2 (21)
- TNNT2 (21)
- TRMT2A (21)
- USP7 (21)
- ACY1 (18)
- CBX8 (18)
- CHEK2 (18)
- CLOCK (18)
- COMMD1 (18)
- CPM (18)
Antibody Hosts
Isotypes
Carrier-free
Knockout (KO) Validation
Families
- Druggable Genome (5763)
- Transcription Factors (1527)
- Transmembrane (1094)
- Protein Kinase (877)
- ES Cell Differentiation/IPS (665)
- Stem cell - Pluripotency (510)
- Protease (496)
- Secreted Protein (326)
- Nuclear Hormone Receptor (126)
- Adult stem cells (108)
- Phosphatase (93)
- Cancer stem cells (69)
- Embryonic stem cells (69)
- Stem cell relevant signaling - DSL/Notch pathway (63)
- Stem cell relevant signaling - JAK/STAT signaling pathway (60)
- P450 (48)
- Induced pluripotent stem cells (39)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (33)
- GPCR (30)
- Ion Channels: Other (24)
- Stem cell relevant signaling - Wnt Signaling pathway (12)
- Ion Channels: Cys-loop Receptors (9)
- Ion Channels: Potassium (6)
Pathways
- Metabolic pathways (1352)
- Pathways in cancer (860)
- Focal adhesion (611)
- MAPK signaling pathway (577)
- ErbB signaling pathway (492)
- Prostate cancer (488)
- Colorectal cancer (470)
- Neurotrophin signaling pathway (443)
- Insulin signaling pathway (429)
- Endometrial cancer (408)
- B cell receptor signaling pathway (405)
- Fc epsilon RI signaling pathway (405)
- Toll-like receptor signaling pathway (405)
- Regulation of actin cytoskeleton (401)
- T cell receptor signaling pathway (387)
- Pancreatic cancer (381)
- Progesterone-mediated oocyte maturation (381)
- Acute myeloid leukemia (372)
- Renal cell carcinoma (369)
- Non-small cell lung cancer (366)
- Glioma (347)
- Chronic myeloid leukemia (339)
- Melanoma (338)
- Fc gamma R-mediated phagocytosis (309)
- Chemokine signaling pathway (306)
- GnRH signaling pathway (300)
- VEGF signaling pathway (297)
- Bladder cancer (273)
- Natural killer cell mediated cytotoxicity (264)
- Purine metabolism (264)
- Thyroid cancer (240)
- Endocytosis (233)
- Pyrimidine metabolism (225)
- Gap junction (224)
- Small cell lung cancer (219)
- Apoptosis (213)
- Melanogenesis (213)
- Oocyte meiosis (213)
- Wnt signaling pathway (212)
- Adherens junction (204)
- Leukocyte transendothelial migration (201)
- mTOR signaling pathway (198)
- Cell cycle (192)
- Type II diabetes mellitus (192)
- Jak-STAT signaling pathway (186)
- Prion diseases (186)
- Alzheimer's disease (183)
- Long-term potentiation (183)
- Arginine and proline metabolism (179)
- Long-term depression (177)
- Glycolysis / Gluconeogenesis (174)
- Vascular smooth muscle contraction (171)
- Ubiquitin mediated proteolysis (162)
- Amyotrophic lateral sclerosis (ALS) (153)
- Valine (150)
- leucine and isoleucine degradation (150)
- Dorso-ventral axis formation (147)
- Phosphatidylinositol signaling system (141)
- Parkinson's disease (135)
- Adipocytokine signaling pathway (132)
- Epithelial cell signaling in Helicobacter pylori infection (132)
- Tight junction (132)
- Calcium signaling pathway (131)
- Fatty acid metabolism (123)
- Inositol phosphate metabolism (123)
- Pathogenic Escherichia coli infection (120)
- DNA replication (114)
- Axon guidance (111)
- Huntington's disease (108)
- Butanoate metabolism (105)
- RNA degradation (105)
- TGF-beta signaling pathway (105)
- Mismatch repair (102)
- Nucleotide excision repair (102)
- Spliceosome (99)
- Base excision repair (96)
- Lysine degradation (96)
- Alanine (90)
- Basal cell carcinoma (90)
- aspartate and glutamate metabolism (90)
- Oxidative phosphorylation (87)
- Propanoate metabolism (87)
- Tryptophan metabolism (86)
- Dilated cardiomyopathy (84)
- Hypertrophic cardiomyopathy (HCM) (84)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (81)
- Cell adhesion molecules (CAMs) (78)
- Primary immunodeficiency (78)
- Proteasome (78)
- Pyruvate metabolism (75)
- p53 signaling pathway (75)
- Glycine (74)
- serine and threonine metabolism (74)
- ABC transporters (72)
- Glutathione metabolism (69)
- Tyrosine metabolism (68)
- Arachidonic acid metabolism (66)
- One carbon pool by folate (66)
- Pentose phosphate pathway (66)
- beta-Alanine metabolism (66)
- Drug metabolism - cytochrome P450 (65)
- PPAR signaling pathway (63)
- Cytokine-cytokine receptor interaction (62)
- Hedgehog signaling pathway (62)
- Histidine metabolism (62)
- Glycerolipid metabolism (60)
- Notch signaling pathway (60)
- Cardiac muscle contraction (57)
- NOD-like receptor signaling pathway (57)
- Amino sugar and nucleotide sugar metabolism (54)
- Terpenoid backbone biosynthesis (54)
- Antigen processing and presentation (51)
- Fatty acid elongation in mitochondria (51)
- Metabolism of xenobiotics by cytochrome P450 (48)
- Starch and sucrose metabolism (48)
- Fructose and mannose metabolism (45)
- RIG-I-like receptor signaling pathway (45)
- Citrate cycle (TCA cycle) (42)
- Vibrio cholerae infection (42)
- Lysosome (39)
- Neuroactive ligand-receptor interaction (39)
- Circadian rhythm - mammal (38)
- Folate biosynthesis (36)
- Galactose metabolism (36)
- Maturity onset diabetes of the young (36)
- Nicotinate and nicotinamide metabolism (36)
- Retinol metabolism (36)
- Synthesis and degradation of ketone bodies (36)
- SNARE interactions in vesicular transport (33)
- Type I diabetes mellitus (33)
- ECM-receptor interaction (30)
- Hematopoietic cell lineage (30)
- N-Glycan biosynthesis (30)
- Regulation of autophagy (30)
- Renin-angiotensin system (30)
- Complement and coagulation cascades (28)
- Methane metabolism (27)
- RNA polymerase (27)
- Systemic lupus erythematosus (25)
- Porphyrin and chlorophyll metabolism (24)
- Ribosome (24)
- Cysteine and methionine metabolism (21)
- Cytosolic DNA-sensing pathway (21)
- Glyoxylate and dicarboxylate metabolism (21)
- Homologous recombination (21)
- Selenoamino acid metabolism (21)
- Aminoacyl-tRNA biosynthesis (18)
- Nitrogen metabolism (18)
- Sulfur metabolism (18)
- Viral myocarditis (18)
- Phenylalanine metabolism (17)
- Androgen and estrogen metabolism (15)
- Ascorbate and aldarate metabolism (15)
- Caffeine metabolism (15)
- Drug metabolism - other enzymes (15)
- Other glycan degradation (15)
- Primary bile acid biosynthesis (15)
- Sphingolipid metabolism (15)
- Fatty acid biosynthesis (12)
- Glycerophospholipid metabolism (12)
- Pantothenate and CoA biosynthesis (12)
- Vitamin B6 metabolism (12)
- Cyanoamino acid metabolism (9)
- Limonene and pinene degradation (9)
- Non-homologous end-joining (9)
- Taurine and hypotaurine metabolism (9)
- Biosynthesis of unsaturated fatty acids (6)
- D-Glutamine and D-glutamate metabolism (6)
- Ether lipid metabolism (6)
- O-Glycan biosynthesis (6)
- Olfactory transduction (6)
- Steroid biosynthesis (6)
- Taste transduction (6)
- Thiamine metabolism (6)
- Allograft rejection (3)
- Autoimmune thyroid disease (3)
- Basal transcription factors (3)
- Glycosaminoglycan degradation (3)
- Glycosphingolipid biosynthesis - lacto and neolacto series (3)
- Graft-versus-host disease (3)
- Keratan sulfate biosynthesis (3)
- Linoleic acid metabolism (3)
- Protein export (3)
- Riboflavin metabolism (3)