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Category
Target Symbol
- MAP2K1 (27)
- MAP2K3 (10)
- TP53 (9)
- CTNNB1 (7)
- EPN2 (7)
- UBE2G2 (7)
- ACAA2 (6)
- AKT1 (6)
- IGF2BP2 (6)
- PARVA (6)
- DNAJA2 (5)
- HSPD1 (5)
- NONO (5)
- PRKCE (5)
- SNX9 (5)
- VBP1 (5)
- ATP5F1B (4)
- BCAR1 (4)
- DDX39B (4)
- DSTN (4)
- EPHX1 (4)
- HDAC6 (4)
- HSPA1A (4)
- MAPK1 (4)
- NRBP1 (4)
- PIK3R5 (4)
- SERPINA1 (4)
- SSB (4)
- TRIM38 (4)
- ACAT2 (3)
- AK4 (3)
- BECN1 (3)
- EIF2S1 (3)
- FBXO21 (3)
- FERMT2 (3)
- FMR1 (3)
- GOLM1 (3)
- GTF3C4 (3)
- HRAS (3)
- ILVBL (3)
- MAPK9 (3)
- MSI1 (3)
- NLN (3)
- NXNL2 (3)
- PFKP (3)
- PPP5C (3)
- PSMA4 (3)
- PSMB9 (3)
- RAB21 (3)
- RNF113B (3)
- RPA2 (3)
- SAMHD1 (3)
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- SERBP1 (3)
- SIGLEC9 (3)
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- CTH (2)
- DDT (2)
- DEF6 (2)
- DNM1L (2)
- DPP9 (2)
- FGG (2)
- GPI (2)
- IDH1 (2)
- KLK8 (2)
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- LIMK1 (2)
- LMAN1 (2)
- LZIC (2)
- MTIF3 (2)
- NDUFB10 (2)
- NHEJ1 (2)
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- PDIA4 (2)
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- PIK3CG (2)
- PMEL (2)
- PSMA2 (2)
- PSMA6 (2)
- PSMB7 (2)
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- RPN1 (2)
- RUVBL2 (2)
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Antibody Hosts
Isotypes
Clonalities
Knockout (KO) Validation
Families
- Druggable Genome (340)
- Protein Kinase (77)
- Transcription Factors (66)
- Transmembrane (49)
- Protease (43)
- Stem cell - Pluripotency (37)
- ES Cell Differentiation/IPS (33)
- Secreted Protein (15)
- Adult stem cells (3)
- Stem cell relevant signaling - DSL/Notch pathway (3)
- Induced pluripotent stem cells (2)
- P450 (2)
- Stem cell relevant signaling - JAK/STAT signaling pathway (2)
- Cancer stem cells (1)
- Ion Channels: Potassium (1)
- Ion Channels: Transient receptor potential (1)
- Nuclear Hormone Receptor (1)
- Phosphatase (1)
Pathways
- MAPK signaling pathway (74)
- Pathways in cancer (73)
- Focal adhesion (68)
- Fc epsilon RI signaling pathway (67)
- Endometrial cancer (65)
- Prostate cancer (65)
- Colorectal cancer (64)
- Metabolic pathways (62)
- Neurotrophin signaling pathway (62)
- Chronic myeloid leukemia (60)
- Toll-like receptor signaling pathway (60)
- Glioma (58)
- Melanoma (58)
- Non-small cell lung cancer (58)
- Pancreatic cancer (58)
- Insulin signaling pathway (56)
- ErbB signaling pathway (55)
- T cell receptor signaling pathway (55)
- Fc gamma R-mediated phagocytosis (54)
- Thyroid cancer (53)
- Acute myeloid leukemia (52)
- Chemokine signaling pathway (52)
- Regulation of actin cytoskeleton (51)
- GnRH signaling pathway (50)
- Progesterone-mediated oocyte maturation (50)
- VEGF signaling pathway (50)
- B cell receptor signaling pathway (49)
- Renal cell carcinoma (49)
- Bladder cancer (47)
- Natural killer cell mediated cytotoxicity (45)
- Melanogenesis (43)
- Gap junction (42)
- Vascular smooth muscle contraction (39)
- Prion diseases (38)
- Long-term depression (37)
- Long-term potentiation (37)
- Oocyte meiosis (33)
- Dorso-ventral axis formation (32)
- Apoptosis (24)
- Amyotrophic lateral sclerosis (ALS) (23)
- Wnt signaling pathway (22)
- Small cell lung cancer (21)
- Tight junction (21)
- mTOR signaling pathway (20)
- Endocytosis (19)
- Leukocyte transendothelial migration (19)
- Type II diabetes mellitus (19)
- Huntington's disease (18)
- Basal cell carcinoma (16)
- Parkinson's disease (16)
- Pathogenic Escherichia coli infection (15)
- Alzheimer's disease (14)
- Cell cycle (14)
- Jak-STAT signaling pathway (14)
- Proteasome (14)
- Adherens junction (13)
- p53 signaling pathway (13)
- Fatty acid metabolism (12)
- Valine (12)
- leucine and isoleucine degradation (12)
- Ubiquitin mediated proteolysis (11)
- Axon guidance (10)
- Adipocytokine signaling pathway (9)
- NOD-like receptor signaling pathway (9)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (8)
- Glycolysis / Gluconeogenesis (8)
- Oxidative phosphorylation (8)
- Spliceosome (8)
- Complement and coagulation cascades (7)
- Fatty acid elongation in mitochondria (7)
- Metabolism of xenobiotics by cytochrome P450 (7)
- RNA degradation (7)
- Antigen processing and presentation (6)
- Cell adhesion molecules (CAMs) (6)
- Hematopoietic cell lineage (6)
- Pentose phosphate pathway (6)
- Phosphatidylinositol signaling system (6)
- Purine metabolism (6)
- TGF-beta signaling pathway (6)
- Type I diabetes mellitus (6)
- Alanine (5)
- Amino sugar and nucleotide sugar metabolism (5)
- Butanoate metabolism (5)
- Epithelial cell signaling in Helicobacter pylori infection (5)
- Galactose metabolism (5)
- RIG-I-like receptor signaling pathway (5)
- Systemic lupus erythematosus (5)
- Tryptophan metabolism (5)
- aspartate and glutamate metabolism (5)
- Arachidonic acid metabolism (4)
- DNA replication (4)
- Drug metabolism - cytochrome P450 (4)
- Glutathione metabolism (4)
- Histidine metabolism (4)
- Lysine degradation (4)
- Mismatch repair (4)
- Nucleotide excision repair (4)
- Primary immunodeficiency (4)
- Pyruvate metabolism (4)
- Regulation of autophagy (4)
- Renin-angiotensin system (4)
- Terpenoid backbone biosynthesis (4)
- Tyrosine metabolism (4)
- Base excision repair (3)
- Cysteine and methionine metabolism (3)
- Fructose and mannose metabolism (3)
- Homologous recombination (3)
- Lysosome (3)
- Propanoate metabolism (3)
- Pyrimidine metabolism (3)
- Retinol metabolism (3)
- Selenoamino acid metabolism (3)
- Synthesis and degradation of ketone bodies (3)
- Vibrio cholerae infection (3)
- Arginine and proline metabolism (2)
- Citrate cycle (TCA cycle) (2)
- Folate biosynthesis (2)
- Glycine (2)
- Glycosaminoglycan degradation (2)
- Inositol phosphate metabolism (2)
- Methane metabolism (2)
- N-Glycan biosynthesis (2)
- Nitrogen metabolism (2)
- Non-homologous end-joining (2)
- Starch and sucrose metabolism (2)
- beta-Alanine metabolism (2)
- serine and threonine metabolism (2)
- Aminoacyl-tRNA biosynthesis (1)
- Androgen and estrogen metabolism (1)
- Basal transcription factors (1)
- Biosynthesis of unsaturated fatty acids (1)
- Caffeine metabolism (1)
- Cardiac muscle contraction (1)
- Cytokine-cytokine receptor interaction (1)
- Cytosolic DNA-sensing pathway (1)
- Drug metabolism - other enzymes (1)
- Glycosphingolipid biosynthesis - ganglio series (1)
- Linoleic acid metabolism (1)
- Maturity onset diabetes of the young (1)
- Notch signaling pathway (1)
- One carbon pool by folate (1)
- Other glycan degradation (1)
- Pantothenate and CoA biosynthesis (1)
- Phenylalanine metabolism (1)
- RNA polymerase (1)
- SNARE interactions in vesicular transport (1)
- Sphingolipid metabolism (1)
- Steroid biosynthesis (1)
- Sulfur metabolism (1)
- Taurine and hypotaurine metabolism (1)
- Viral myocarditis (1)