Mutant ORF Clones

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NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402173

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C988Y), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C988Y
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402174

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C997G), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C997G
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402175

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C1004Y), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C1004Y
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402176

USD 3,910.00

3 Weeks

NOTCH3 Mutant (R1006C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	R1006C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402177

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C1015R), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C1015R
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402178

USD 3,910.00

3 Weeks

NOTCH3 Mutant (A1020P), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	A1020P
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402179

USD 3,910.00

3 Weeks

NOTCH3 Mutant (Y1021C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	Y1021C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402180

USD 3,910.00

3 Weeks

NOTCH3 Mutant (R1031C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	R1031C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402181

USD 3,910.00

3 Weeks

NOTCH3 Mutant (G1058C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	G1058C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402182

USD 3,910.00

3 Weeks

NOTCH3 Mutant (R1076C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	R1076C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402183

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C1099Y), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C1099Y
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402184

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C1131W), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C1131W
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402185

USD 3,910.00

3 Weeks

NOTCH3 Mutant (R1231C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	R1231C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402186

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C1261Y), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C1261Y
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402187

USD 3,910.00

3 Weeks

NOTCH3 Mutant (C1261R), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	C1261R
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

NOTCH3 (NM_000435) Human Mutant ORF Clone

RC402188

USD 3,910.00

3 Weeks

NOTCH3 Mutant (L1515P), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA

Mutation	L1515P
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402649

USD 670.00

2 Weeks

MAP2K1 Mutant (E44G), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	E44G
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402650

USD 670.00

2 Weeks

MAP2K1 Mutant (F53S), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	F53S
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402651

USD 670.00

2 Weeks

MAP2K1 Mutant (T55P), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	T55P
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402654

USD 670.00

2 Weeks

MAP2K1 Mutant (P124Q), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	P124Q
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402656

USD 670.00

2 Weeks

MAP2K1 Mutant (Y130C), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	Y130C
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402657

USD 670.00

2 Weeks

MAP2K1 Mutant (Y130N), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	Y130N
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

MEK1 (MAP2K1) (NM_002755) Human Mutant ORF Clone

RC402658

USD 670.00

2 Weeks

MAP2K1 Mutant (E203Q), Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) as transfection-ready DNA

Mutation	E203Q
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

EGFR (NM_005228) Human Mutant ORF Clone

RC402760

USD 2,040.00

3 Weeks

EGFR Mutant (R521K), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA

Mutation	R521K
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

EGFR (NM_005228) Human Mutant ORF Clone

RC402761

USD 2,040.00

3 Weeks

EGFR Mutant (G796S), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA

Mutation	G796S
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

EGFR (NM_005228) Human Mutant ORF Clone

RC402762

USD 2,040.00

3 Weeks

EGFR Mutant (V843I), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA

Mutation	V843I
Vector	pCMV6-Entry
Tag	Myc-DDK
Mammalian Cell Selection	Neomycin

TrueORF^®

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cDNA Clones

Mutant ORF Clones

NOTCH3

EGFR

KRAS

MAP2K1

Human

Myc-DDK

pCMV6-Entry

Yes

Neomycin

Druggable Genome

Protein Kinase

Adult stem cells

Cancer stem cells

ES Cell Differentiation/IPS

Secreted Protein

Stem cell relevant signaling - JAK/STAT signaling pathway

Transmembrane

Pathways in cancer

Colorectal cancer

Insulin signaling pathway

Endometrial cancer

Pancreatic cancer

Mismatch repair

Prostate cancer

Melanoma

Thyroid cancer

Glioma

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

mTOR signaling pathway

p53 signaling pathway

Non-small cell lung cancer

Ubiquitin mediated proteolysis

Chronic myeloid leukemia

MAPK signaling pathway

Focal adhesion

Bladder cancer

Neurotrophin signaling pathway

Metabolic pathways

Type II diabetes mellitus

ErbB signaling pathway

Regulation of actin cytoskeleton

Endocytosis

Primary immunodeficiency

Renal cell carcinoma

Homologous recombination

Small cell lung cancer

Amino sugar and nucleotide sugar metabolism

Galactose metabolism

Glycolysis / Gluconeogenesis

Maturity onset diabetes of the young

Starch and sucrose metabolism

Natural killer cell mediated cytotoxicity

Dorso-ventral axis formation

Chemokine signaling pathway

Acute myeloid leukemia

Melanogenesis

Long-term depression

T cell receptor signaling pathway

Gap junction

Wnt signaling pathway

Apoptosis

VEGF signaling pathway

GnRH signaling pathway

Cell cycle

Tight junction

Basal cell carcinoma

Long-term potentiation

Progesterone-mediated oocyte maturation

Notch signaling pathway

Adherens junction

Vascular smooth muscle contraction

Leukocyte transendothelial migration

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Huntington's disease

Fc gamma R-mediated phagocytosis

Jak-STAT signaling pathway

Inositol phosphate metabolism

Calcium signaling pathway

Cytokine-cytokine receptor interaction

Toll-like receptor signaling pathway

Adipocytokine signaling pathway

Axon guidance

Citrate cycle (TCA cycle)

Vibrio cholerae infection

Pathogenic Escherichia coli infection

Epithelial cell signaling in Helicobacter pylori infection

Dilated cardiomyopathy

Taste transduction

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Nucleotide excision repair

Prion diseases

TGF-beta signaling pathway

Oocyte meiosis

Cell adhesion molecules (CAMs)

Glutathione metabolism

Neuroactive ligand-receptor interaction

Base excision repair

Metabolism of xenobiotics by cytochrome P450

Complement and coagulation cascades

Hematopoietic cell lineage

PPAR signaling pathway

TrueORF

Yes

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Mutant ORF Clones

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