shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
CHRNA4 Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors BMC Cancer, 2015 Mar shRNA TG313920
CHRNA7 Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory α 7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm Oxidative Medicine and Cellular Longevity, 2022 Jan shRNA TG313917
CHRNA7 Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression Int. Immunopharmacol., 2015 May shRNA TR313917
CHRNA7 Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors BMC Cancer, 2015 Mar shRNA TG313917
CHRNA9 Molecular mechanisms of synergy of corneal muscarinic and nicotinic acetylcholine receptors in upregulation of E-cadherin expression Int. Immunopharmacol., 2015 May shRNA TR305392
CHRNA9 Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors BMC Cancer, 2015 Mar shRNA TG305392
CIITA Pollen-induced antigen presentation by mesenchymal stem cells and T cells from allergic rhinitis Clinical & Translational Immunology (2013) 2, e7, 2013 Oct shRNA TR313899
CISH MicroRNA-98 and let-7 Confer Cholangiocyte Expression of Cytokine-Inducible Src Homology 2-Containing Protein in Response to Microbial Challenge J. Immunol., Aug 2009; 183: 1617 - 1624, 2009 Aug shRNA TR316498
CITED1 CITED1 promotes proliferation of papillary thyroid cancer cells via the regulation of p21 and p27 Cell Biosci, 2018 Nov shRNA TR313896
CKAP4 The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer Cell Death Dis, 2019 Aug shRNA TG506478
Ckmt1 A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling The EMBO Journal, 2023 Feb shRNA TF512727
CLDN1 Claudin-1 induces epithelial–mesenchymal transition through activation of the c-Abl-ERK signaling pathway in human liver cells Oncogene doi: 10.1038/onc.2012.505, 2012 Nov shRNA TR305370
Cldn3 Claudin-4 is required for AMPK-modulated paracellular permeability in submandibular gland cells J Mol Cell Biol, 2014 Dec shRNA TG711499
Cldn4 Claudin-4 is required for AMPK-modulated paracellular permeability in submandibular gland cells J Mol Cell Biol, 2014 Dec shRNA TG701533
Cltc Clathrin Assembly Defines the Onset and Geometry of Cortical Patterning Dev. Cell2017, 2017 Nov shRNA TF710306
Cltc Dysregulation of nectin-2 in the testicular cells: An explanation of cadmium-induced male infertility Biochim. Biophys. Acta July 2014, 2014 Jul shRNA TG516542
CNR1 The role of CB1 in intestinal permeability and inflammation The FASEB Journal, 2017 Apr shRNA TR316500
CNR1 Cannabinoid Receptors Modulate Neuronal Morphology and AnkyrinG Density at the Axon Initial Segment Front Cell Neurosci, 2017 Feb shRNA TG512614
CNR1 Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy Diabetes, Sep 2011; 60: 2386 - 2396., 2011 Oct shRNA TR316500
CNTNAP2 The CNTNAP2-CASK complex modulates GluA1 subcellular distribution in interneurons Neurosci. Lett., 2019 Feb shRNA TG510300
CNTNAP2 CNTNAP2 stabilizes interneuron dendritic arbors through CASK Mol. Psychiatry, 2018 Apr shRNA TG510300
Cntnap2 Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2 /Caspr2 knockout neurons Proceedings of the National Academy of Sciences of the United States of America, 2015 May shRNA TL510300
COG4 Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene PNAS, Aug 2009; 106: 13329 - 13334, 2009 Aug shRNA TR317052
Col1a2 Targeting the secreted RGDKGE collagen fragment reduces PD‑L1 by a proteasome‑dependent mechanism and inhibits tumor growth. Oncology reports, 2023 Feb shRNA TL500407
COL23A1 Collagen XXIII: A Potential Biomarker for the Detection of Primary and Recurrent Non–Small Cell Lung Cancer Cancer Epidemiol. Biomarkers Prev., May 2010; 19: 1362 - 1372, 2010 May shRNA TR317712
COL6A1 Mutant p53 Together with TGFß Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer Clin. Cancer Res., 2016 Sep shRNA TF500404
COL6A1 Mutant p53 Together with TGFß Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer Clin. Cancer Res., 2016 Sep shRNA MG223027
COMMD7 COMMD7 is correlated with a novel NF-?B positive feedback loop in hepatocellular carcinoma Oncotarget, 2016 May shRNA TR305276
COPRS Myc and Omomyc functionally associate with the Protein Arginine Methyltransferase 5 (PRMT5) in glioblastoma cells Sci Rep, 2015 Nov shRNA TF306098
COPS5 Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells Br. J. Cancer, 2015 May shRNA TR313776
COQ4 Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency J. Med. Genet., Mar 2012; 49: 187 - 191., 2012 Mar shRNA TR305264
CPT1C Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress Genes & Dev., May 2011; 25: 1041 - 1051, 2011 May shRNA TR305235
CRBN Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41 Cancer Research, 2016 Apr shRNA TG305228
CREB1 Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics Transl Psychiatry, 2019 Nov shRNA TG313740
CREB1 Genetic Evidence for Critical Roles of P38a Protein in Regulating Mast Cell Differentiation and Chemotaxis through Distinct Mechanisms J. Biol. Chem., Jun 2012; 287: 20258 - 20269., 2012 Jan shRNA TR313740
CREB3L3 Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell Rep, 2019 Jul shRNA TF513785
CREBBP Epigenetic modifiers promote mitochondrial biogenesis and oxidative metabolism leading to enhanced differentiation of neuroprogenitor cells Cell Death Dis, 2018 Mar shRNA TF712619
CREBBP Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer Nature Genetics 44, 1104-1110 doi:10.1038/ng.2396, 2012 Sep shRNA TR313738
CREG1 CREG1 promotes lysosomal biogenesis and function Autophagy, 2021 May shRNA TF510293
Creg1 CREG promotes vasculogenesis by activation of VEGF/PI3K/Akt pathway Frontiers in Bioscience, 2014 Jun shRNA TG510293
CRYAB Inhibition of the Expression of the Small Heat Shock Protein aB-crystallin Inhibits Exosome Secretion in Human Retinal Pigment Epithelial Cells in Culture J. Biol. Chem., 2016 Apr shRNA TG313715
CSF1 miR-1254 inhibits progression of glioma in vivo and in vitro by targeting CSF-1 J. Cell. Mol. Med., 2020 Jan shRNA TG305200
CSF1 Colony-stimulating factor 1 potentiates lung cancer bone metastasis Lab. Invest., Jan 2014., 2014 Jan shRNA TG305200
CSF2 Autophagy inhibition by sustained over-production of IL-6 contributes to arsenic-induced carcinogenesis Cancer Res., 2014 May shRNA TF313703
CSF2 Immune-Dependent and Independent Antitumor Activity of GM-CSF Aberrantly Expressed by Mouse and Human Colorectal Tumors Cancer Res., Jan 2013; 73: 395 - 405., 2013 Jan shRNA MC208342
Csk Decreased levels of RGS4 in the paraventricular nucleus facilitate GABAergic inhibition during the acute stress response. Biochemical and biophysical research communications, 2016 Aug shRNA TG510981
CSK SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines Am J Pathol. 2007 Jan;170(1):366-76., 2007 Jan shRNA TR320311
CSMD1 Loss of CSMD1 expression is associated with high tumour grade and poor survival in invasive ductal breast carcinoma Breast Cancer Res Treat DOI 10.1007/s10549-009-0500-4, 2009 Aug shRNA TR305196
CSNK2A1 Transcriptional Regulation of PIK3CD and PIKFYVE in T-Cell Acute Lymphoblastic Leukemia by IKAROS and Protein Kinase CK2 International journal of molecular sciences, 2021 Jan shRNA TG320317
CSNK2A1 Regulation of Small GTPase Rab20 by Ikaros in B-Cell Acute Lymphoblastic Leukemia Int J Mol Sci, 2020 Mar shRNA TG514070