siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
CYP1A1 Role of AHR, NF-kB and CYP1A1 crosstalk with the X protein of Hepatitis B virus in hepatocellular carcinoma cells. Gene, 2023 Jan siRNA SR301093
CYP1A1 Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway Nat Commun, 2019 Jan siRNA SR301093
Cyp1a1 LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPAR? ligand synthesis Nat Commun, 2015 Apr siRNA SR416691
Cyp1b1 LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPAR? ligand synthesis Nat Commun, 2015 Apr siRNA SR417055
CYP1B1 7,12-Dimethylbenzanthracene induces apoptosis in RL95-2 human endometrial cancer cells: ligand-selective activation of cytochrome P450 1B1. Toxicology and applied pharmacology, 2012 Aug siRNA SR301095
CYP27A1 Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells The Journal of Biological Chemistry, 2023 Jul siRNA SR301124
CYP2J2 CYP2J2 Modulates Diverse Transcriptional Programs in Adult Human Cardiomyocytes Sci Rep, 2020 Mar siRNA SR301109
CYP2J2 CYP2J2 expression in adult ventricular myocytes protects against external and drug induced ROS toxicity Drug Metab. Dispos., 2018 Jan siRNA SR301109
CYP7A1 Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRa signalling pathway in oxLDL-loaded macrophages J. Cell. Mol. Med., 2016 Sep siRNA SR319873
CYSLTR1 1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Oncotarget, 2019 Jun siRNA SR307365
CYSLTR1 1,4-dihydroxy Quininib Attenuates Growth of Colorectal Cancer Cells and Xenografts and Regulates the TIE-2 Signaling Pathway in Patient Tumours bioRxiv, 2018 Dec siRNA SR035004
DAAM1 Kif26b controls endothelial cell polarity through the Dishevelled/Daam1-dependent planar cell polarity–signaling pathway Molecular Biology of the Cell, 2016 Mar siRNA SR307929
DAB2 Podosome formation promotes plasma membrane invagination and integrin-β3 endocytosis on a viscous RGD-membrane Commun Biol, 2020 Mar siRNA SR505444
DCC Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats J Am Heart Assoc, 2017 May siRNA SR502160
DCLK1 Doublecortin-Like Kinase 1 (DCLK1) Is a Novel NOTCH Pathway Signaling Regulator in Head and Neck Squamous Cell Carcinoma Frontiers in Oncology, 2021 Jul siRNA SR306088
DDB1 The RepID-CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation Nat Commun, 2020 Jan siRNA SR301160
DDIT3 Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer J. Exp. Clin. Cancer Res., 2018 Nov siRNA SR319903
DDIT3 Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma Br. J. Cancer, 2018 Jun siRNA SR319903
DDIT3 Withaferin A Induces Cell Death Selectively in Androgen-Independent Prostate Cancer Cells but Not in Normal Fibroblast Cells PLoS ONE, 2015 Aug siRNA SR301166
DDR1 The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension Communications Biology, 2023 Aug siRNA SR319533
DEPTOR Cell cycle genes are downregulated after adipogenic triggering in human adipose tissue-derived stem cells by regulation of mRNA abundance Sci Rep, 2019 Apr siRNA SR312133
DHCR24 Dhcr24 activates the PI3K/Akt/HKII pathway and protects against dilated cardiomyopathy in mice Anim Models Exp Med, 2018 Mar siRNA SR416496
DHFR DHFR/TYMS are positive regulators of glioma cell growth and modulate chemo-sensitivity to temozolomide Eur. J. Pharmacol., 2019 Sep siRNA SR301197
DHFR Towards Identifying Novel Modulators and Targets for Alzheimer's Disease Therapy Thesis, 2014 Jul siRNA SR301197
DICER1 Identification of PTBP1 responsible for caspase dependent YRNA cleavage bioRxiv, 2018 Apr siRNA SR323577
DKK1 A Succinate Ether Derivative of Tocotrienol Enhances Dickkopf-1 Gene Expression through Epigenetic Alterations in Malignant Mesothelioma Cells Pharmacology, 2018 May siRNA SR323463
DKK3 A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis BMC Cancer, 2017 Mar siRNA SR308986
DLG1 SAP97 blocks the RXR ER retention signal of NMDA receptor subunit GluN1-3 through its SH3 domain Biochim. Biophys. Acta, 2014 Dec siRNA SR301211
DLGAP5 Hepatoma upregulated protein expression is involved in the pathogenesis of human breast carcinogenesis Oncol Lett, 2014 Oct siRNA SR306548
DLK1 LncRNA LINC01315 silencing modulates cancer stem cell properties and epithelial-to-mesenchymal transition in colorectal cancer via miR-484/DLK1 axis. Cell cycle (Georgetown, Tex.), 2022 Apr siRNA SR305789
DLK1 The adaptor SASH1 acts through NOTCH1 and its inhibitor DLK1 in a 3D model of lumenogenesis involving CEACAM1 Exp. Cell Res., 2017 Aug siRNA SR305789
DLL1 Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture Sci Rep, 2019 Jul siRNA SR509346
DMPK The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target Oncotarget, 2017 Dec siRNA SR301227
DNAJC10 IRE1 prevents endoplasmic reticulum membrane permeabilization and cell death under pathological conditions Sci Signal, 2015 Jun siRNA SR512297
DNM1L Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles Am. J. Physiol. Heart Circ. Physiol, 2017 Mar siRNA SR306774
DNM2 Podosome formation promotes plasma membrane invagination and integrin-β3 endocytosis on a viscous RGD-membrane Commun Biol, 2020 Mar siRNA SR501378
DNM2 Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein Naunyn Schmiedebergs Arch. Pharmacol., 2016 Jul siRNA SR301243
DNMT1 DAXX Suppresses Tumor-Initiating Cells in Estrogen Receptor-positive Breast Cancer following endocrine therapy Cancer Res., 2019 Aug siRNA SR301244
DNMT1 LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation EBioMedicine, 2018 Sep siRNA SR301244
DNMT1 The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts Oncotarget, 2018 Jan siRNA SR301244
DNMT3A Cyclic AMP Response Element Modulator-α Suppresses PD-1 Expression and Promotes Effector CD4+ T Cells in Psoriasis Journal of immunology (Baltimore, Md. : 1950) 2021, 2021 Jun siRNA SR319937
DNMT3A Prognostic significance of DNMT3A alterations in Middle Eastern papillary thyroid carcinoma European Journal of Cancer, 2019 Aug siRNA SR319937
DNMT3A LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation EBioMedicine, 2018 Sep siRNA SR319937
DNMT3A Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells FEBS Lett., 2016 Apr siRNA SR301246
DNMT3a cAMP responsive element modulator (CREM)a mediates chromatin remodeling of CD8 during the generation of CD3+CD4-CD8- T cells J. Biol. Chem. Dec 2013., 2013 Dec siRNA SR301246
DNMT3a cAMP response element modulator a controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus PNAS, Oct 2012; 109: 16606 - 16611., 2012 Oct siRNA SR301246
DNMT3B LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation EBioMedicine, 2018 Sep siRNA SR301247
Drd1 Spinal dopaminergic D 1 and D 5 receptors contribute to reserpine-induced fibromyalgia-like pain in rats. Brain research, 2022 Dec siRNA SR502135
DRD2 Tumor suppressor DRD2 facilitates M1 macrophages and restricts NF-κB signaling to trigger pyroptosis in breast cancer Theranostics, 2021 Mar siRNA SR319948
Drd5 Spinal dopaminergic D 1 and D 5 receptors contribute to reserpine-induced fibromyalgia-like pain in rats. Brain research, 2022 Dec siRNA SR502866