shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
CSNK2A1 Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide Oncogene, 2019 Aug shRNA TG320317
CSNK2A1 Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia Oncotarget, 2017 Jan shRNA TG320317
CTCF Identification of CTCF as a master regulator of the clustered protocadherin genes Nucleic Acids Res., Dec 2011; 10.1093/nar/gkr1260., 2011 Dec shRNA TR313675
CTCFL Downregulation of BORIS/CTCFL leads to ROS-dependent cellular senescence and drug sensitivity in MYCN-amplified neuroblastoma. The FEBS journal, 2022 May shRNA TR305184
CTCFL BORIS Binding to the Promoters of Cancer Testis Antigens, MAGEA2, MAGEA3, and MAGEA4, Is Associated with Their Transcriptional Activation in Lung Cancer Clin. Cancer Res., Jul 2011; 17: 4267 - 4276., 2011 Jul shRNA TR305184
CTCFL Widespread Expression of BORIS/CTCFL in Normal and Cancer Cells PLoS ONE, 2011 Jul shRNA TG305184
CTCFL BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression Mol. Cell. Biol. 2008; 28(21): p. 6720-6729, 2008 Oct shRNA TR305184
CTCFL DNA Methyltransferase 1 and 3B Activate BAG-1 Expression via Recruitment of CTCFL/BORIS and Modulation of Promoter Histone Methylation Cancer Res., Apr 2008; 68: 2726 - 2735, 2008 Apr shRNA TR305184
CTH Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis EMBO Rep., 2019 Aug shRNA TF313670
CTNNB1 Cell dynamics in Hertwig\'s epithelial root sheath are regulated by β-catenin activity during tooth root development Journal of cellular physiology, 2020 Dec shRNA TG500280
CTNNB1 Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death Cell Death Dis, 2018 Feb shRNA TG313664
CTNNB1 ß-Catenin Activates the HOXA10 and CDX4 Genes in Myeloid Progenitor Cells J. Biol. Chem., Nov 2012; 287: 39589 - 39601., 2012 Nov shRNA TG313664
Ctnnb1 HSulf-1 inhibits cell proliferation and invasion in human gastric cancer. Cancer science, 2012 Jan shRNA TL711793
CTNND1 P120ctn may participate in epithelial-mesenchymal transition in OSCC Indian J Cancer, 2016 May shRNA TF313663
CTNND2 d-Catenin promotes prostate cancer cell growth and progression by altering cell cycle and survival gene profiles Molecular Cancer 2009, 8:19, 2009 Mar shRNA TR313662
CTR9 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Oct 2012; 209: 2099 - 2111., 2012 Oct shRNA TG313659
CTR9 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification J. Exp. Med., Sep 2012; 10.1084/jem.20112145., 2012 Sep shRNA TR313659
CTSA Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1 PLoS Genet., 2014 Feb shRNA TF501716
CTSL Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model Int. J. Cancer, 2016 Jan shRNA TG305172
CUL5 Cullin 5 is a novel candidate tumor suppressor in renal cell carcinoma involved in the maintenance of genome stability Oncogenesis, 2019 Jan shRNA TR313638
custom BCL2 Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability Br. J. Cancer, Feb 2014., 2014 Feb shRNA
custom OMA1 Stress-triggered Activation of the Metalloprotease Oma1 Involves its C-terminal Region and is Important for Mitochondrial Stress Protection in Yeast J. Biol. Chem., 2014 Mar shRNA
custom VPU The Expression of HIV-1 Vpu in Monocytes Causes Increased Secretion of TGF-β that Activates Profibrogenic Genes in Hepatic Stellate Cells PLoS ONE, Feb 2014., 2014 Feb shRNA
Cx3cr1 Emergent role of the fractalkine axis in dissemination of peritoneal metastasis from epithelial ovarian carcinoma Oncogene, 2016 Dec shRNA TR509718
CXCL10 Tumor-Suppressive Effects of Natural-type Interferon-ß through CXCL10 in Melanoma Biochem. Biophys. Res. Commun., 2015 Jun shRNA TG313633
CXCL12 CXCL12 secreted from glioma stem cells regulates their proliferation J. Neurooncol., Jan 2014., 2014 Jan shRNA TR501994
CXCL17 The role and clinical significance of the CXCL17-CXCR8 (GPR35) axis in breast cancer. Biochemical and biophysical research communications, 2017 Oct shRNA TL307883
CXCL8 A Novel TNF-mediated Mechanism of Direct Epithelial Sodium Channel Activation Am. J. Respir. Crit. Care Med. July 2014, 2014 Jul shRNA TG319476
CXCL8 Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells Oncotarget July 2014, 2014 Jul shRNA TG319476
CXCR1 IL-8, GRO and MCP-1 produced by hepatocellular carcinoma microenvironment determine the migratory capacity of human bone marrow-derived mesenchymal stromal cells without affecting tumor aggressiveness Oncotarget, 2017 Oct shRNA TG312158
CXCR2 IL-8, GRO and MCP-1 produced by hepatocellular carcinoma microenvironment determine the migratory capacity of human bone marrow-derived mesenchymal stromal cells without affecting tumor aggressiveness Oncotarget, 2017 Oct shRNA TG312157
CXCR2 CXCR2 Expression in Tumor Cells Is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma Cancer Res., Jan 2013; 73: 571 - 582., 2013 Jan shRNA TG312157
CXCR4 EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma Nat Commun, 2015 Sep shRNA TR313630
CYBB Early and Late Events Induced by PolyQ-expanded Proteins: IDENTIFICATION OF A COMMON PATHOGENIC PROPERTY OF POLYQ-EXPANDED PROTEINS J. Biol. Chem., Feb 2011; 286: 4727 - 4741, 2011 Feb shRNA TR313616
CYGB Cytoglobin, the Newest Member of the Globin Family, Functions as a Tumor Suppressor Gene Cancer Research 68, 7448, September 15, 2008, 2008 Sep shRNA TR305139
Cyp11a1 Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease PNAS, May 2013; 110: 8152 - 8157., 2013 May shRNA TG500467
CYP19A1 Brain-synthesized estrogens regulate cortical migration in a sexually divergent manner BioRxiv, 2019 May shRNA TG509276
CYP3A4 Cytochrome P450 3A5 Plays a Prominent Role in the Oxidative Metabolism of the Anti-Human Immunodeficiency Virus Drug Maraviroc Drug Metabolism and Disposition, 2013 Dec shRNA TL305124
CYTH1 A critical role of Arf6 in the response of commissural axons to Slit Development, 2019 Jan shRNA TR517243
CYTH2 A critical role of Arf6 in the response of commissural axons to Slit Development, 2019 Jan shRNA TR501756
CYTH3 A critical role of Arf6 in the response of commissural axons to Slit Development, 2019 Jan shRNA TR501757
DAPK1 Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria Nat Commun, 2017 Oct shRNA TF504327
DDR1 Tumor DDR1 deficiency reduces liver metastasis by colon carcinoma and impairs stromal reaction American journal of physiology. Gastrointestinal and liver physiology, 2021 Apr shRNA TG320280
DDR1 Discoidin Domain Receptor 1 functionally interacts with the IGF-I system in bladder cancer Matrix Biology Plus, 2020 Jan shRNA TG320280
DDR2 Amplification of DDR2 mediates sorafenib resistance through NF-κB/c-Rel signaling in hepatocellular carcinoma Cell biology international, 2021 May shRNA TG320440
DDR2 DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1 J. Exp. Clin. Cancer Res., 2015 Sep shRNA TR320440
DDX56 Oncogenic splicing abnormalities induced by DEAD-Box Helicase 56 amplification in colorectal cancer Cancer Sci., 2019 Oct shRNA TR307148
DDX58 Measles Virus V Protein Inhibits NLRP3 Inflammasome-Mediated Interleukin-1ß Secretion J. Virol., Dec 2011; 85: 13019 - 13026., 2011 Dec shRNA TR313514
DDX6 The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs Nucleic Acids Res., 2015 Mar shRNA TG313512
DEDD Regulation of the HPV-18 E6/E6AP Ubiquitin Ligase Complex by the HECT domain-containing protein EDD J. Virol., Jan 2011; 10.1128/JVI.02004-10, 2011 Jan shRNA TR313510