siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
DROSHA Identification of PTBP1 responsible for caspase dependent YRNA cleavage bioRxiv, 2018 Apr siRNA SR309202
DROSHA Novel functional small RNAs are selectively loaded onto mammalian Ago1 Nucleic Acids Res., 2014 Mar siRNA SR309202
DSC3 Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer Exp. Cell Res., 2019 May siRNA SR301278
DSC3 The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer Carcinogenesis, Dec 2012; 33: 2326 - 2333., 2012 Dec siRNA SR421036
DSG2 Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome Oncotarget, 2016 Jul siRNA SR301282
DSG2 A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis Angiogenesis, 2016 Jun siRNA SR301282
DSP Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/ß-catenin signaling pathway in human lung cancer Carcinogenesis, Oct 2012; 33: 1863 - 1870., 2012 Oct siRNA SR301285
DTNA Dystrobrevin alpha gene is a direct target of the vitamin D receptor in muscle J. Mol. Endocrinol., 2020 Jan siRNA SR419093
DUSP1 Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors J. Immunol., 2016 Sep siRNA SR301295
DUSP16 Angiotensin II induces connective tissue growth factor expression in human hepatic stellate cells by a transforming growth factor β-independent mechanism Sci Rep, 2017 Aug siRNA SR312968
DUSP4 Modulation of p38 kinase by DUSP4 Is important in regulating cardiovascular function under oxidative stress Free Radic. Biol. Med., 2015 Jul siRNA SR508955
DUSP4 Redox Activation of DUSP4 by N-Acetyl Cysteine Protects Endothelial Cells from Cd(2+)-Induced Apoptosis Free Radic. Biol. Med., 2014 Jun siRNA SR508955
DVL1 DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage J Neuroinflammation, 2020 Apr siRNA SR419232
DYRK1A REST Regulates DYRK1A Transcription in a Negative Feedback Loop J. Biol. Chem., Mar 2011; 286: 10755 - 10763, 2011 Mar siRNA SR301308
E2F1 E2F1 activates MFN2 expression by binding to the promoter and decreases mitochondrial fission and mitophagy in HeLa cells FEBS J., 2019 Jul siRNA SR301310
EDA Ectodysplasin-A mRNA in exosomes released from activated hepatic stellate cells stimulates macrophage response. Experimental cell research, 2022 Sep siRNA SR301325
EGFR Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021 Mar siRNA SR418750
EGFR EGFR activity addiction facilitates anti-ERBB based combination treatment of squamous bladder cancer Oncogene, 2020 Sep siRNA SR320009
EGFR Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo Biomaterials, 2019 Apr siRNA SR320009
EGFR Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells Transl Oncol, 2018 Aug siRNA SR301357
EGFR MiR-615 inhibits cell proliferation, migration and invasion by targeting EGFR in human glioblastoma Biochem. Biophys. Res. Commun., 2018 May siRNA SR320009
EGFR Novel tumor suppressor microRNA at frequently deleted chromosomal region 8p21 regulates epidermal growth factor receptor in prostate cancer Oncotarget, 2016 Oct siRNA SR301357
EGFR Celecoxib-erlotinib combination delays growth and inhibits angiogenesis in EGFR-mutated lung cancer Am J Cancer Res, 2016 Aug siRNA SR301357
EGR1 c‑Jun and FOXO1 mediate the expression of oncogenic PKC‑ι in human prostate cancer cells with an interplay between NF‑κB, IL‑8 and ICAM‑1 World Acad Sci J, 2020 Jun siRNA SR320010
EGR1 FOXO1 regulates oncogenic PKC-ι expression in melanoma inversely to c-Jun in an autocrine manner via IL-17E and ICAM-1 activation wasj, 2017 Oct siRNA SR320010
EIF2A GCN2 reduces inflammation by p-eIF2α/ATF4 pathway after intracerebral hemorrhage in mice Exp. Neurol., 2018 Dec siRNA SR415709
EIF2A Distinctive subcellular inhibition of cytokine-induced SRC by salubrinal and fluid flow PLoS ONE, 2014 Aug siRNA SR313291
EIF2AK2 Knockdown of HIP1 expression promotes ligand‑induced endocytosis of EGFR in HeLa cells Oncol. Rep., 2017 Oct siRNA SR303767
EIF2AK2 AIM2 Inflammasome Mediates Arsenic-induced Secretion of IL-1 beta and IL-18 OncoImmunology, 2016 Mar siRNA SR303767
EIF2AK3 MicroRNA-494 Regulates Endoplasmic Reticulum Stress in Endothelial Cells Frontiers in Cell and Developmental Biology, 2021 Jul siRNA SR306267
EIF2AK3 A miR-494 dependent feedback loop regulates ER stress bioRxiv, 2020 May siRNA SR306267
EIF2AK3 HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer Oncogenesis, 2019 Aug siRNA SR306267
EIF2AK3 Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells J. Cell. Physiol., 2018 Aug siRNA SR306267
Eif2ak3 Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness Oncotarget, 2017 Oct siRNA SR422112
EIF2AK3 Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response Cancer Res., Sep 2012; 72: 4696 - 4706., 2012 Sep siRNA SR306267
EIF2AK4 Oxidative Stress Triggers Selective tRNA Retrograde Transport in Human Cells during the Integrated Stress Response Cell Rep, 2019 Mar siRNA SR318498
EIF3B EIF3B silencing inhibits cell proliferation via regulating EGFR/ERK pathway in lung adenocarcinoma Int J Clin Exp Patho, 2016 Nov siRNA SR305696
EIF4E Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS -mutant lung cancer Journal of Experimental & Clinical Cancer Research : CR, 2022 Jan siRNA SR320018
EIF4E HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer Oncogenesis, 2019 Aug siRNA SR320018
Eif4g2 The thyroid hormone increases bulk histones expression by enhancing translational efficiency Mol. Endocrinol., 2014 Nov siRNA SR421103
ELF1 Indirect regulation of TFPI-2 expression by miR-494 in breast cancer cells Sci Rep, 2020 Mar siRNA SR301385
ELK3 LRG1 promotes keratinocyte migration and wound repair through regulation of HIF-1α stability J. Invest. Dermatol., 2019 Jul siRNA SR301391
ELK3 LRG1 promotes keratinocyte migration and wound repair through regulation of HIF-1α stability J. Invest. Dermatol., 2019 Jul siRNA SR413593
ELOVL5 Polyunsaturated fatty acid elongation and desaturation in activated human T cells: ELOVL5 is the key elongase J. Lipid Res., 2018 Oct siRNA SR311827
EMD Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus Nat Commun, 2020 May siRNA SR301395
EP300 Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling Proc. Natl. Acad. Sci. U.S.A., 2014 Sep siRNA SR301414
EPAS1 Defining the role of oxygen tension in human neural progenitor fate Stem Cell Reports, 2014 Nov siRNA SR301415
EPAS1 Hypoxia Inducible Regulation of Placental BOK Expression Biochem. J., 2014 May siRNA SR301415
EPG5 The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity Autophagy, 2017 Nov siRNA SR311692
EPRS EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice Nature, 2017 Feb siRNA SR422951