shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
Depdc5 DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting Cell reports, 2022 Sep shRNA TL508165
Depdc5 DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting Cell reports, 2022 Sep shRNA TL705799
DEPDC5 DEPDC5 and NPRL3 modulate cell size, filopodial outgrowth, and localization of mTOR in neural progenitor cells and neurons Neurobiol. Dis., 2018 Feb shRNA TG508165
DIAPH3 mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formation bioRxiv, 2019 Aug shRNA TG304992
Dicer1 Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis Theranostics, 2020 Jan shRNA TL514154
DICER1 Impaired DICER1 function promotes stemness and metastasis in colon cancer Oncogene. 2013 Oct 7., 2013 Oct shRNA TR304991
Dicer1 Aging-Induced Dysregulation of Dicer1-Dependent MicroRNA Expression Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells J Gerontol A Biol Sci Med Sci, Aug 2013; 68: 877 - 891., 2013 Aug shRNA TR304991
DICER1 Aging-Induced Dysregulation of Dicer1-Dependent MicroRNA Expression Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells J Gerontol A Biol Sci Med Sci, Dec 2012; 10.1093/gerona/gls242., 2012 Dec shRNA TG304991
DICER1 Dicer-Mediated Upregulation of BCRP Confers Tamoxifen Resistance in Human Breast Cancer Cells Clin. Cancer Res., Oct 2011; 17: 6510 - 6521., 2011 Oct shRNA TR304991
DKK1 A Positive Feedback Loop Regulates the Expression of Polycomb Group Protein BMI1 via WNT Signaling Pathway J. Biol. Chem., Feb 2013; 288: 3406 - 3418., 2013 Feb shRNA TG313465
DKK1 Tobacco Smoke Induces Polycomb-Mediated Repression of Dickkopf-1 in Lung Cancer Cells Cancer Res., Apr 2009; 69: 3570 - 3578, 2009 Apr shRNA TR313465
Dkk3 DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways. International journal of oncology, 2019 May shRNA TL502835
DLAT Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation Cell Rep, 2018 Nov shRNA TG507127
DLC1 Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas J. Neurooncol, 2016 Dec shRNA TG304982
DLG1 Differential Regulation of Two Isoforms of the Glial Glutamate Transporter EAAT2 by DLG1 and CaMKII J. Neurosci., 2015 Apr shRNA TF313458
DLG4 Spatial coupling tunes NMDA receptor responses via Ca2+ diffusion J. Neurosci., 2019 Sep shRNA TG710382
DLGAP5 Prognostic value of DLGAP5 in colorectal cancer Int J Colorectal Dis, 2019 Aug shRNA TG316879
Dll1 Notch1 regulated autophagy controls survival and suppressor activity of activated murine T-regulatory cells Elife, 2016 Jun shRNA TG500534
DLL4 Delta-like ligand 4 in hepatocellular carcinoma intrinsically promotes tumour growth and suppresses hepatitis B virus replication World J. Gastroenterol., 2018 Sep shRNA TG304977
DLL4 Amyloid-β precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit α type-5 and proteasome subunit β type-7. Neurobiology of aging, 2015 Sep shRNA TF304977
DLX3 Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell Rep, 2019 Jul shRNA TF500537
DLX4 The Homeoprotein DLX4 Stimulates NF-?B Activation and CD44-Mediated Tumor-Mesothelial Cell Interactions in Ovarian Cancer Am. J. Pathol., 2015 Jun shRNA TG313449
DLX4 Homeodomain protein DLX4 counteracts key transcriptional control mechanisms of the TGF-ß cytostatic program and blocks the antiproliferative effect of TGF-ß Oncogene (7 February 2011) doi:10.1038/onc.2011.4 Original Article, 2011 Feb shRNA TR313449
DNAIC2 Dynein axonemal intermediate chain 2 plays a role in gametogenesis by activation of Stat3 J. Cell. Mol. Med., 2018 Nov shRNA TR517468
DNM2 Bovine Ephemeral Fever Virus Uses a Clathrin-Mediated and Dynamin 2-Dependent Endocytosis Pathway That Requires Rab5 and Rab7 as Well as Microtubules J. Virol., Dec 2012; 86: 13653 - 13661., 2012 Dec shRNA TG313406
DNM2 Cell Entry of Avian Reovirus Follows a Caveolin-1-mediated and Dynamin-2-dependent Endocytic Pathway That Requires Activation of p38 Mitogen-activated Protein Kinase (MAPK) and Src Signaling Pathways as Well as Microtubules and Small GTPase Rab5 Protein J. Biol. Chem., Sep 2011; 286: 30780 - 30794., 2011 Oct shRNA TG313406
DNMBP Tuba activates Cdc42 during neuronal polarization downstream of the small GTPase Rab8a bioRxiv, 2019 Dec shRNA TF515449
DNMT1 Endoplasmic reticulum protein 29 (ERp29) confers radioresistance through the DNA repair gene, O 6 -methylguanine DNA-methyltransferase, in breast cancer cells Scientific Reports, 2015 Sep shRNA TF313404
DNMT1 CD66+ cells in cervical pre-cancers are partially differentiated progenitors with neoplastic traits Cancer Res., 2014 Sep shRNA TR313404
DNMT1 Cell Entry of Avian Reovirus Follows a Caveolin-1-mediated and Dynamin-2-dependent Endocytic Pathway That Requires Activation of p38 Mitogen-activated Protein Kinase (MAPK) and Src Signaling Pathways as Well as Microtubules and Small GTPase Rab5 Protein The Journal of Biological Chemistry, 2011 Sep shRNA TG313404
DNMT3A Dnmt3a is required for the tumor stemness of B16 melanoma cells Acta Biochim. Biophys. Sin. (Shanghai) 2019, 2019 Aug shRNA TF304938
DPYSL2 A Collapsin Response Mediator Protein 2 Isoform Controls Myosin II-Mediated Cell Migration and Matrix Assembly by Trapping ROCK II Mol. Cell. Biol., May 2012; 32: 1788 - 1804., 2012 May shRNA TR313374
DSP Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/ß-catenin signaling pathway in human lung cancer Carcinogenesis, Aug 2012; 10.1093/carcin/bgs226., 2012 Aug shRNA TR313354
DUOX2 Contribution of Dual Oxidase 2 (DUOX2) to Hyper-Radiosensitivity in Human Gastric Cancer Cells Radiat. Res., 2015 Aug shRNA TR313350
DUOXA1 Dual Oxidase Maturation factor 1 (DUOXA1) overexpression increases reactive oxygen species production and inhibits murine muscle satellite cell differentiation Cell Commun. Signal, Jan 2014., 2014 Jan shRNA TR304888
DUSP10 mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma Genes Cancer, 2014 Nov shRNA TG304883
Dusp10 Co-inhibition of NF-?B and JNK is synergistic in TNF-expressing human AML J. Exp. Med., 2014 May shRNA TG513100
DUSP19 USP17 regulates Ras activation and cell proliferation by blocking RCE 1 activity J. Biol. Chem., Feb 2009; 10.1074/jbc.M807216200., 2009 Apr shRNA TR304880
Dusp2 Co-inhibition of NF-?B and JNK is synergistic in TNF-expressing human AML J. Exp. Med., 2014 May shRNA TG514083
DUSP4 Statins affect ETS1-overexpressing triple-negative breast cancer cells by restoring DUSP4 deficiency Sci Rep, 2016 Sep shRNA TG304875
Dusp6 Co-inhibition of NF-?B and JNK is synergistic in TNF-expressing human AML J. Exp. Med., 2014 May shRNA TG514782
E2F1 An E2F1/MiR-17-92 Negative Feedback Loop mediates proliferation of Mouse Palatal Mesenchymal Cells Sci Rep, 2017 Jul shRNA TG509487
E2F1 Cooperative Activation of Tissue-Specific Genes by pRB and E2F1 Cancer Res., Apr 2013; 73: 2150 - 2158., 2013 Apr shRNA TG320325
E2F1 Transcriptional Regulation of the Human Tumor Suppressor DOK1 by E2F1 Mol. Cell. Biol., Dec 2012; 32: 4877 - 4890., 2012 Dec shRNA TG320325
E2F6 A comprehensive ChIP-chip analysis of E2F1, E2F4, and E2F6 in normal and tumor cells reveals interchangeable roles of E2F family members Genome Res. 2007 Nov;17(11):1550-61., 2007 Nov shRNA TR316522
EDD Regulation of the Human Papillomavirus Type 18 E6/E6AP Ubiquitin Ligase Complex by the HECT Domain-Containing Protein EDD J. Virol., Apr 2011; 85: 3120 - 3127, 2011 Apr shRNA
EDEM1 Innate Sensing of Influenza A Virus Hemagglutinin Glycoproteins by the Host Endoplasmic Reticulum (ER) Stress Pathway Triggers a Potent Antiviral Response via ER-Associated Protein Degradation Journal of Virology, 2018 Jan shRNA TL313302
EGFP The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability Nucleic Acids Res., 2018 Mar shRNA TR30001
EGFR Expression level of EGFR and MET receptors regulates invasiveness of melanoma cells J. Cell. Mol. Med., 2019 Dec shRNA TG320326
EGFR Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers Cell Stem Cell, 2019 May shRNA TR509941