siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
ERBB2 HER2 Impedes MLK3 Kinase Activity to Support Breast Cancer Cell Survival J. Biol. Chem., 2015 Jul siRNA SR301443
ERBB2 A novel function of HER2/Neu in the activation of G2/M checkpoint in response to ?-irradiation Oncogene, 2014 Jun siRNA SR301443
ERBB3 ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood-brain-barrier modulation Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021 Feb siRNA SR320065
ERBB3 Human Papillomavirus Regulates HER3 Expression in Head and Neck Cancer: Implications for Targeted HER3 Therapy in HPV+ Patients Clin. Cancer Res., 2017 Jun siRNA SR320065
ERBB3 A novel function of HER2/Neu in the activation of G2/M checkpoint in response to ?-irradiation Oncogene, 2014 Jun siRNA SR301444
ERBB4 EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics Cell, 2017 Oct siRNA SR320066
ERBB4 Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells Cell Cycle, 2015 Feb siRNA SR301445
ERCC6 ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB Nat Commun, 2018 Oct siRNA SR320072
ERN1 A miR-494 dependent feedback loop regulates ER stress bioRxiv, 2020 May siRNA SR320074
ERN1 Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells J. Cell. Physiol., 2018 Aug siRNA SR320074
Ern1 Unfolded protein response signaling impacts macrophage polarity to modulate breast cancer cell clearance and melanoma immune checkpoint therapy responsiveness Oncotarget, 2017 Oct siRNA SR421536
ERN1 MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer Mol. Cancer, 2014 Oct siRNA SR301457
ERO1A Endoplasmic Reticulum Oxidase 1α is Critical for Collagen Secretion from and Membrane Type 1-Matrix Metalloproteinase levels in Hepatic Stellate Cells J. Biol. Chem., 2017 Aug siRNA SR309340
ERRFI1 Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation EMBO Rep., 2018 Mar siRNA SR310045
ESR1 Crosstalk between progesterone receptor membrane component 1 and estrogen receptor α promotes breast cancer cell proliferation Laboratory investigation; a journal of technical methods and pathology, 2021 Apr siRNA SR301461
ESR1 Estrogenic and anti-inflammatory effects of pseudoprotodioscin in atherosclerosis-prone mice: Insights into endothelial cells and perivascular adipose tissues Eur. J. Pharmacol., 2019 Dec siRNA SR418015
ESR1 Estrogenic and anti-inflammatory effects of pseudoprotodioscin in atherosclerosis-prone mice: Insights into endothelial cells and perivascular adipose tissues Eur. J. Pharmacol., 2019 Dec siRNA SR301461
ESR1 Hypoxia-induced secretion stimulates breast cancer stem cell regulatory signalling pathways Mol Oncol, 2019 May siRNA SR301461
ESR1 Aminophenols increase proliferation of thyroid tumor cells by inducing the transcription factor activity of estrogen receptor α Biomed. Pharmacother., 2018 Nov siRNA SR418015
ESR1 Six1 promotes colorectal cancer growth and metastasis by stimulating angiogenesis and recruiting tumor-associated macrophages Carcinogenesis, 2017 Feb siRNA SR301461
ESR1 Transcription factor activity of estrogen receptor a activation upon nonylphenol or bisphenol A treatment enhances the in vitro proliferation, invasion, and migration of neuroblastoma cells Onco Targets Ther, 2016 Jul siRNA SR301461
ESR1 17ß-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cells BMC Cancer, 2015 May siRNA SR301461
ESR1 Estrogen regulation of anti-apoptotic bcl-2 family member mcl-1 expression in breast cancer cells PLoS ONE, 2014 Jun siRNA SR301461
ESR1 Oestrogen induced downregulation of TFPI expression is mediated by ERa Thrombosis Research . April 2014, 2014 Apr siRNA SR301461
ESR2 GPER1 promotes estrogen receptor negative breast cancer cell migration and invasion via non-genomic activation of c-Src/NF-κB/focal adhesion kinase cascade Journal of Bio-X Research, 2018 Sep siRNA SR301462
ESRRA Repression of the transcriptional activity of ERRα with sequence-specific DNA-binding polyamides Med Chem Res, 2020 Feb siRNA SR414015
ETS1 ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling Sci Rep, 2015 Mar siRNA SR301470
ETS2 Membrane-bound β-catenin degradation is enhanced by ETS2-mediated Siah1 induction in Helicobacter pylori-infected gastric cancer cells Oncogenesis, 2017 May siRNA SR301471
ETS2 ETS2 and Twist1 promote invasiveness of Helicobacter pylori-infected gastric cancer cells by inducing Siah2 Biochem. J., 2016 Apr siRNA SR301471
EXOSC10 Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis Cell Rep, 2015 Nov siRNA SR420984
EXOSC5 Chromatin Dynamics and the RNA Exosome Function in Concert to Regulate Transcriptional Homeostasis Cell Rep, 2015 Nov siRNA SR406507
EXTL3 REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway Communications biology, 2021 Jun siRNA SR421199
EZH2 Flow-dependent epigenetic regulation of IGFBP5 expression by H3K27me3 contributes to endothelial anti-inflammatory effects Theranostics, 2018 May siRNA SR320099
EZH2 MiR-101 Targets the EZH2/Wnt/ß-Catenin the Pathway to Promote the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells Sci Rep, 2016 Nov siRNA SR301494
EZH2 Modulation of EZH2 expression by MEK-ERK or PI3K-AKT signaling in lung cancer is dictated by different KRAS oncogene mutations Cancer Res., 2015 Dec siRNA SR301494
EZH2 VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy Clin. Cancer Res., 2014 May siRNA SR301494
F2R Tetracyclines promote survival and fitness in mitochondrial disease models Nature metabolism, 2021 Jan siRNA SR301496
FAM111A Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components Nat. Cell Biol., Feb 2014., 2014 Feb siRNA SR311883
FAM114A2 Genetic association of primary non-response to Anti-TNFα therapy in patients with Inflammatory Bowel Disease medRxiv, 2020 Jun siRNA SR307384
FAM20C Fam20C‐mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis FASEB j., 2019 Nov siRNA SR511577
FAM20C Functional analysis of mutant FAM20C in Raine syndrome with FGF23-related hypophosphatemia Bone July 2014, 2014 Jul siRNA SR511577
FBXO6 Fbxo6 confers drug-sensitization to cisplatin via inhibiting the activation of Chk1 in non-small cell lung cancer FEBS Lett., 2019 May siRNA SR308802
FBXW7 Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells Oncogenesis, 2017 Jul siRNA SR310654
Fbxw7 MicroRNA-27b exerts an oncogenic function by targeting Fbxw7 in human hepatocellular carcinoma Tumour Biol., 2016 Oct siRNA SR310654
FCGR2A CD163 and IgG Codefend against Cytotoxic Hemoglobin via Autocrine and Paracrine Mechanisms J. Immunol., May 2013; 190: 5267 - 5278., 2013 May siRNA SR301549
FCGR3A CD163 and IgG Codefend against Cytotoxic Hemoglobin via Autocrine and Paracrine Mechanisms J. Immunol., May 2013; 190: 5267 - 5278., 2013 May siRNA SR301551
FGF1 MiR-205-5p suppresses angiogenesis in gastric cancer by downregulating the expression of VEGFA and FGF1 Experimental Cell Research, 2021 May siRNA SR301569
FGF1 INAVA promotes aggressiveness of papillary thyroid cancer by upregulating MMP9 expression Cell Biosci, 2018 Apr siRNA SR301569
FGF5 A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma Journal of Biological Chemistry, 2017 Apr siRNA SR301573
FGFR1 Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS ‐mutant cancer EMBO Molecular Medicine, 2021 Aug siRNA SR320159