shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
EGFR Modification of cytokine-induced killer cells with chimeric antigen receptors (CARs) enhances antitumor immunity to epidermal growth factor receptor (EGFR)-positive malignancies Cancer Immunol. Immunother., 2015 Sep shRNA TG320326
EGFR EGFR signaling defines Mcl(-)1 survival dependency in neuroblastoma Cancer Biol. Ther., 2015 Feb shRNA TG320326
EGFR Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development J. Biol. Chem., 2014 Dec shRNA TG320326
EGFR Optical methodology for detecting histologically unapparent nanoscale consequences of genetic alterations in biological cells PNAS. published 10 December 2008, 10.1073/pnas.0804723105, 2008 Dec shRNA TR320326
EGFR Polyethylene glycol-mediated colorectal cancer chemoprevention: roles of epidermal growth factor receptor and Snail Mol. Cancer Ther., Sep 2008; 7: 3103 - 3111, 2008 Sep shRNA TR320326
EGR3 Opposing role for egr3 in nucleus accumbens cell subtypes in cocaine action J. Neurosci., 2015 May shRNA TG500585
Ehmt2 Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent Progenitors Stem Cells International May 2015, 1905 May shRNA TG505922
EIF2AK2 Identification of the PKR Nuclear Interactome Reveals Roles in Ribosome Biogenesis, mRNA Processing and Cell Division J. Cell. Physiol. Dec 2013., 2013 Dec shRNA TG320493
Eif2ak4 Genetic or Pharmacological Reduction of PERK Enhances Cortical-Dependent Taste Learning J. Neurosci., 2014 Oct shRNA TG511649
EIF4A1 miR-133a acts as a tumor suppressor in colorectal cancer by targeting eIF4A1 Tumour Biol., 2017 May shRNA TG313247
ELAVL1 The alternative spliced 3'-UTR mediated differential secretion of macrophage colony stimulating factor in breast cancer cells Biochem. Biophys. Res. Commun., 2020 Mar shRNA TR313235
ELAVL1 Posttranscriptional Suppression of Proto-Oncogene c-fms Expression by Vigilin in Breast Cancer Mol. Cell. Biol., Jan 2011; 31: 215 - 225, 2011 Jan shRNA TR313235
ELAVL1 Post-Transcriptional Suppression of Proto-Oncogene c-fms Expression by Vigilin in Breast Cancer Mol. Cell. Biol., Oct 2010; 10.1128/MCB.01031-10, 2010 Oct shRNA TR313235
ELAVL1 Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer Oncogene (19 Jan 2009), doi: 10.1038/onc.2008.469, 2009 Jan shRNA TR313235
ELAVL4 Prenatal Deletion of the RNA-Binding Protein HuD Disrupts Postnatal Cortical Circuit Maturation and Behavior J. Neurosci., 2014 Mar shRNA TG501025
ELAVL4 The role of HuD, a post-transcriptional regulator, in the development and function of the murine neocortex Thesis. January 2014, 2014 Jan shRNA TG501025
ELF3 A transcriptional repressive role for epithelial-specific ETS factor ELF3 on estrogen receptor-alpha in breast cancer cells BIOCHEMICAL JOURNAL, 2016 Feb shRNA TG313232
ELK1 GADD45a-Targeted Suicide Gene Therapy for the Prevention or Treatment of Non-Small Cell Lung Carcinoma Thesis, 2015 Jun shRNA TR320328
ELMO1 A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis Nat. Immunol., 2019 Feb shRNA TG320622
EMILIN1 EMILIN1–a4/a9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation J. Cell Biol., Sep 2011; 10.1083/jcb.201008013., 2011 Oct shRNA TR510314
EMX2 EMX2 Is a Predictive Marker for Adjuvant Chemotherapy in Lung Squamous Cell Carcinomas PLoS ONE, 2015 Jul shRNA TF313216
EMX2 EMX2 is epigenetically silenced and suppresses growth in human lung cancer Oncogene (9 August 2010) doi:10.1038/onc.2010.330 Short Communication, 2010 Aug shRNA TR313216
ENPP1 Antagonistic interactions between osterix and pyrophosphate during cementum formation Bone, 2019 May shRNA TG501613
Entpd1 cAMP/CREB-mediated Transcriptional Regulation of Ectonucleoside Triphosphate Diphosphohydrolase 1 (CD39) Expression J. Biol. Chem., May 2010; 285: 14791 - 14805, 2010 May shRNA TR500312
EP300 Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKT Int. J. Biol. Sci., 2020 Mar shRNA TG313197
EP300 ANALYSIS OF THE UPSTREAM SIGNALLING PATHWAY CONTROLLING DELTANP63ALPHA PROTEIN STABILITY AND FUNCTION Thesis, 2014 Jan shRNA TR313197
EPAS1 Modulation of the mevalonate pathway by Akt regulates macrophage survival and development of pulmonary fibrosis J. Biol. Chem., 2014 Nov shRNA TG315484
EPHA2 Progranulin/EphA2 axis: A novel oncogenic mechanism in bladder cancer Matrix Biol., 2020 May shRNA TR320327
EPHA2 EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma Int. J. Cancer, 2018 Mar shRNA TR320327
EPHA2 A Modified Adenovirus Vector-Mediated Antibody Screening Method Identifies EphA2 as a Cancer Target Transl Oncol, 2017 May shRNA TR320327
EPHA2 A Genome-Wide Screen Reveals Functional Gene Clusters in the Cancer Genome and Identifies EphA2 as a Mitogen in Glioblastoma Cancer Res., Nov 2006; 66: 10815-10823., 2006 Nov shRNA TR320327
EPHB2 Effects of Toxicologically Relevant Xenobiotics and the Lipid-Derived Electrophile 4-Hydroxynonenal on Macrophage Cholesterol Efflux: Silencing Carboxylesterase 1 Has Paradoxical Effects on Cholesterol Uptake and Efflux Chem. Res. Toxicol., 2014 Sep shRNA TG320337
EPHB4 Erythropoietin Promotes Bone Formation through EphrinB2/EphB4 Signaling J. Dent. Res., 2015 Jan shRNA TG500619
EPHX2 Pro-Resolving Maresins in Inflammation: New Pathway and Mechanisms With Oral Pathogens Thesis, 2015 Aug shRNA TR313191
EPHX2 Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages PLoS ONE July 2014, 2014 Jul shRNA TR313191
ERAP1 ERAP1 reduces accumulation of aberrant and disulfide-linked forms of HLA-B27 on the cell surface Mol. Immunol., 2016 Apr shRNA TG307017
ERBB3 A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations Proteomics, 2014 Nov shRNA TR320343
ERBB3 microRNA-205 Regulates HER3 in Human Breast Cancer Cancer Res., Mar 2009; 69: 2195 - 2200, 2009 Mar shRNA TR320343
ERCC6 Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane FASEB J, Feb 2010; 10.1096/fj.09-147991, 2010 Feb shRNA TR313176
ERCC6 Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase J. Biol. Chem., Jan 2009; 10.1074/jbc.M807006200., 2009 Apr shRNA TR313176
ERN1 Insulin demand regulates ß cell number via the unfolded protein response J. Clin. Invest., 2015 Oct shRNA TG320345
ERO1A Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer Oncotarget, 2017 Apr shRNA TR313168
ERO1a Hypoxia augments MHC class I antigen presentation via facilitation of ERO1-a-mediated oxidative folding in murine tumor cells Eur. J. Immunol., 2016 Sep shRNA TR502816
ERO1A Cancer-associated oxidoreductase ERO1-a drives the production of VEGF via oxidative protein folding and regulating the mRNA level Br. J. Cancer, 2016 Apr shRNA TR313168
ERO1A Cancer-Associated Oxidase ERO1-a Regulates the Expression of MHC Class I Molecule via Oxidative Folding J. Immunol., 2015 May shRNA TR313168
Ero1a Cancer-associated oxidoreductase ERO1-α drives the production of tumor-promoting myeloid-derived suppressor cells via oxidative protein folding. Journal of immunology (Baltimore, Md. : 1950), 2015 Apr shRNA TR502816
ERO1A Real-time monitoring of redox changes in the mammalian endoplasmic reticulum J. Cell Sci., Jul 2011; 124: 2349 - 2356., 2011 Jul shRNA TR313168
ERRFI1 The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations Oncogene, 2016 Nov shRNA TR304737
ESR1 Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer Oncogene, 2019 Mar shRNA TR320346
ESR1 RIZ1 is regulated by estrogen and suppresses tumor progression in endometrial cancer Biochem. Biophys. Res. Commun., 2017 May shRNA TR320346