shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
ESR1 Knockdown of estrogen receptor-a induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death FASEB J., 2014 May shRNA TR320346
ESR1 Nuclear Localization of the Transcriptional Regulator MIER1a Requires Interaction with HDAC1/2 in Breast Cancer Cells PLoS ONE Dec 2013., 2013 Dec shRNA TG320346
ESR2 Expression of Estrogen Receptor Beta Predicts Oncologic Outcome of pT3 Upper Urinary Tract Urothelial Carcinoma Better Than Aggressive Pathological Features Sci Rep, 2016 Apr shRNA TG320347
ESR2 Biologic Roles of Estrogen Receptor-ß and Insulin-Like Growth Factor-2 in Triple-Negative Breast Cancer BioMed Research International, 2015 Jan shRNA TG320347
Esrrg Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERR{gamma} Nucleic Acids Res., Oct 2008; 36: 5727 - 5735., 2008 Oct shRNA TR502584
Esrrg Transcriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERR Nucleic Acids Res., Sep 2008; 10.1093/nar/gkn567., 2008 Sep shRNA TR502584
Esrrg Orphan nuclear receptor estrogen-related receptor-? suppresses in vitro and in vivo growth of prostate cancer cells via p21WAF1/CIP1 induction and as a potential therapeutic target in prostate cancer Oncogene 27, 3313 - 3328 (10 Dec 2007), 2007 Dec shRNA TR502584
ETS1 ETS1 transcriptional activity is increased in advanced prostate cancer and promotes the castrate-resistant phenotype Carcinogenesis, Mar 2012; 33: 572 - 580., 2012 Mar shRNA TR313153
ETS2 Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion The EMBO Journal, 2012 Jul shRNA TG320351
ETS2 Inactivation of Rb in stromal fibroblasts promotes epithelial cell invasion The EMBO Journal doi:10.1038/emboj.2012.153, 2012 May shRNA TR320351
Etv4 Pea3 Expression Promotes the Invasive and Metastatic Potential of Colorectal Carcinoma World Journal of Gastroenterology July 2014, 2014 Jul shRNA TG509137
EWSR1 Ewing sarcoma breakpoint region 1 prevents transcription-associated genome instability bioRxiv Dec2015, 2015 Dec shRNA TG313142
EXO1 Phospholipase C-ε regulates bladder cancer cells via ATM/EXO1 American journal of cancer research, 2020 Aug shRNA TR304725
Exoc4 CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion Stem Cells, 2016 Jun shRNA TR502000
EXTL3 Regenerating Islet-derived 1a (Reg-1a) Protein Is New Neuronal Secreted Factor That Stimulates Neurite Outgrowth via Exostosin Tumor-like 3 (EXTL3) Receptor J. Biol. Chem., Feb 2012; 287: 4726 - 4739., 2012 Feb shRNA TG313126
EYA1 EYA1's conformation-specificity in dephosphorylating phosphothreonine in Myc and its activity on Myc stabilization in breast cancer Mol. Cell. Biol., 2016 Oct shRNA TR304716
EYA1 Regulation of the innate immune response by threonine-phosphatase of Eyes absent Nature. 2009 Jul 23;460(7254):520-4., 2009 Jul shRNA TR304716
EYA2 Regulation of the innate immune response by threonine-phosphatase of Eyes absent Nature. 2009 Jul 23;460(7254):520-4., 2009 Jul shRNA TR304715
EYA3 Regulation of the innate immune response by threonine-phosphatase of Eyes absent Nature. 2009 Jul 23;460(7254):520-4., 2009 Jul shRNA TR316534
EYA4 Regulation of the innate immune response by threonine-phosphatase of Eyes absent Nature. 2009 Jul 23;460(7254):520-4., 2009 Jul shRNA TR304714
EZH2 Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma The Journal of Clinical Investigation, 2022 May shRNA TL304713
EZH2 Maternal regulation of SATB2 in osteo‐progeniters impairs skeletal development in offspring FASEB j., 2019 Dec shRNA TG509722
EZH2 EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma Nat Commun, 2015 Sep shRNA TR304713
EZH2 C-type lectin-like domain and fibronectin-like type II domain of phospholipase A2 receptor 1 modulate binding and migratory responses to collagen FEBS Lett., 2015 Feb shRNA TG304713
Ezh2 NFIB-Mediated Repression of the Epigenetic Factor Ezh2 Regulates Cortical Development J. Neurosci., Feb 2014., 2014 Feb shRNA TF304713
EZH2 EZH2/miR-30d/KPNB1 pathway regulates malignant peripheral nerve sheath tumor cell survival and tumorigenesis J Pathol. 2013 Oct 16, 2013 Oct shRNA TG304713
EZH2 GATA-1 Utilizes Ikaros and Polycomb Repressive Complex 2 To Suppress Hes1 and To Promote Erythropoiesis Mol. Cell. Biol., Sep 2012; 32: 3624 - 3638., 2012 Sep shRNA TR304713
F11r Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury Neurobiol. Dis., 2014 Mar shRNA TG501134
FABP5 Role of Fatty Acid Binding Protein 5 (FABP5) in Breast Cancer Progression and Metastasis Thesis, 2013 Apr shRNA TG316535
FADD RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy Autophagy, 2015 Jul shRNA TG320593
FADS1 Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD + Recycling Cell metabolism, 2020 Apr shRNA TR313102
FADS2 Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD + Recycling Cell metabolism, 2020 Apr shRNA TR313101
Faf2 A Ubiquitin-like Domain Recruits an Oligomeric Chaperone to a Retrotranslocation Complex in Endoplasmic Reticulum-associated Degradation J. Biol. Chem., Jun 2013; 288: 18068 - 18076., 2013 Jun shRNA TG509324
FAF2 Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets Mol. Biol. Cell, Mar 2012; 23: 800 - 810., 2012 Mar shRNA TR308511
FAIM2 Lifeguard inhibition of Fas-mediated apoptosis: A possible mechanism for explaining the cisplatin resistance of triple-negative breast cancer cells Biomed. Pharmacother., 2016 Feb shRNA TG313099
FAM107A Down-regulated in renal cell carcinoma 1 (DRR1) regulates axon outgrowth during hippocampal neuron development Biochemical and biophysical research communications, 2021 Apr shRNA TG702872
FANCA Upregulated ATM Gene Expression and Activated DNA Crosslink–Induced Damage Response Checkpoint in Fanconi Anemia: Implications for Carcinogenesis Mol Med 14 (3-4) 167-174, 2008 Mar shRNA TR313071
FANCA Ataxia Telangiectasia Mutated (ATM) Gene Expression Is Reversibly Up-Regulated in FANCA-Mutant Patient Fibroblasts by an Indirect Mechanism Blood (ASH Annual Meeting Abstracts), Nov 2007; 110: 1679., 2007 Nov shRNA TR313071
FANCD2 HPV-16 E7 Reveals a Link between DNA Replication Stress, Fanconi Anemia D2 Protein, and Alternative Lengthening of Telomere–Associated Promyelocytic Leukemia Bodies Cancer Res., Dec 2008; 68: 9954 - 9963., 2008 Dec shRNA TR313068
FANCF F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019 Jan shRNA TF304585
FASN Up-Regulated FASN Expression Promotes Transcoelomic Metastasis of Ovarian Cancer Cell through Epithelial-Mesenchymal Transition Int J Mol Sci July 2014, 2014 Jul shRNA TR313058
FBXL5 F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway Biomed. Pharmacother., 2018 Nov shRNA TF304567
FBXO28 LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1 J. Cell. Sci., 2015 Nov shRNA TG313036
Fbxo46 The SCF FBXO46 ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence The Journal of Biological Chemistry, 2018 Aug shRNA TL702960
FCN1 Secreted M-Ficolin Anchors onto Monocyte Transmembrane G Protein-Coupled Receptor 43 and Cross Talks with Plasma C-Reactive Protein to Mediate Immune Signaling and Regulate Host Defense J. Immunol., Dec 2010; 185: 6899 - 6910, 2010 Dec shRNA TR313015
FCRL1 Fc Receptor-Like 1 as a Promising Target for Immunotherapeutic Interventions of B-Cell-Related Disorders Biomark Insights., 2019 Nov shRNA TG304533
FDX1 Mitochondrial Targeting of Cytochrome P450 (CYP) 1B1 and its Role in Polycyclic Aromatic Hydrocarbon-Induced Mitochondrial Dysfunction J. Biol. Chem., Feb 2014., 2014 Feb shRNA TG313008
FFAR1 Regulation of cell survival through free fatty acid receptor 1 (FFA1) and FFA4 induced by endothelial cells in osteosarcoma cells J. Recept. Signal Transduct. Res., 2020 Apr shRNA TR313001
FFAR1 Induction of GPR40 positively regulates cell motile and growth activities in breast cancer MCF-7 cells J. Recept. Signal Transduct. Res., 2018 Aug shRNA TR313001
FFAR1 Involvement of FFA1 and FFA4 in the regulation of cellular functions during tumor progression in colon cancer cells Exp. Cell Res., 2018 May shRNA TF313001